1. LABORATORY MONITORING OF HIV INFECTION SESSION WEPDB01 13:00-14:00 HRS Wednesday, July 25, 2012 7/25/12 SESSION WEPDB01: Laboratory Monitoring of HIV Infection 1

2. Participants Chair – Robert W. Coombs, MD, PhD, FRCPC University of Washington, Seattle, WA POSTER PRESENTORS – WEPDB0101: Howard Gale, MD, MT (ASCP) VA Medical Center, Washington, DC – WEPDB0102: Charlotte Charpentier, PharmD, PhD Laboratoire de Virologie; Hôpital Bichat-Claude Bernard; Paris, France – WEPDB0103: Kenneth Ouma, PhD KEMRI-CDC, Kisumu, Kenya – WEPDB0104: Dana Raugi, MPH University of Washington, Seattle, WA 7/25/12 SESSION WEPDB01: Laboratory Monitoring of HIV Infection 2

3. RULES 5 minute presentation; 2 minutes for clarification 30 minutes for questions & general discussion between the panelists and audience – We will focus on four questions of relevance to the resource-limited setting 7/25/12 SESSION WEPDB01: Laboratory Monitoring of HIV Infection 3

4. Questions LABORATORY MONITORING OF HIV INFECTION: – What is the ideal testing frequency for HIV RNA and CD4 monitoring? VIRAL SUPPRESSION: – What level of HIV-1 RNA defines “virological” failure? DRIED BLOOD SPOTS: – Simple/rapid specimen collection and testing – what is required to validate DBS for HIV RNA/DNA? DUAL HIV-1/-2 INFECTION: – Do we need better dual diagnostic tests for HIV-1/-2? 7/25/12 SESSION WEPDB01: Laboratory Monitoring of HIV Infection 4