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Process Control in Biomanufacturing Mary Jane Kurtz & George Taliadouros Minuteman Regional High School Bioman Conference July 2009.

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Presentation on theme: "Process Control in Biomanufacturing Mary Jane Kurtz & George Taliadouros Minuteman Regional High School Bioman Conference July 2009."— Presentation transcript:

1 Process Control in Biomanufacturing Mary Jane Kurtz & George Taliadouros Minuteman Regional High School Bioman Conference July 2009

2 What is Process Control? Use of instruments to carry out a process Input information : measured variables temperature, oxygen, pH Output directions: manipulated variables heat, pressure gauge, valve

3 Motion and Process Control Motion control – position or velocity Process control – temperature, pressure, flow, level, pH,humidity, chemical compounds Two types of control of either of these –Batch processing –Continuous processing

4 Driving a Car: An Everyday Example of Process Control Control Objective Measured variable Manipulated variable (or controlled variable)‏ Sensor Actuator Controller Disturbance Maintain car in lane Location on the road Steering of car Driver’s eyes Driver’s arms/steering wheel Driver Curve in the road

5 Open Loop Control Valve controls flow of water: Open Loop

6 Closed Loop Control Control Process : Closed Loop

7 Process Control Diagram Error detector Error signal controller Controller output signal Actuator Energy or Fuel Manufacturing process Controlled variable Measured variable Disturbances Measurement devices Feedback Signal Set Point +-

8 Importance of Process Control for the Bio-Process Industries Improved product quality Faster and less expensive process validation Increased production rates

9 Biomanufacturing Tanks

10 DO Control in a Bio-Reactor

11 Controlling a Process Using Robolab you will learn how to control a process using a computer You will begin with a simple task : How to start and stop a fan How to control the variables in the process Finally, you will be create a program that will control a greenhouse

12 RBX Controls Inputs are measured variables seen as numbers Temperature sensor Touch sensor Light sensor Outputs are manipulated variables seen as letters Motor light

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14 Time to Try it Out !!! Go to Robo Lab station and try to make a fan


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