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Insulin Secretory Response Is Positively Associated with the Extent of Ossification of the Posterior Longitudinal Ligament of the Spine by Toru Akune,

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Presentation on theme: "Insulin Secretory Response Is Positively Associated with the Extent of Ossification of the Posterior Longitudinal Ligament of the Spine by Toru Akune,"— Presentation transcript:

1 Insulin Secretory Response Is Positively Associated with the Extent of Ossification of the Posterior Longitudinal Ligament of the Spine by Toru Akune, Naoshi Ogata, Atsushi Seichi, Isao Ohnishi, Kozo Nakamura, and Hiroshi Kawaguchi J Bone Joint Surg Am Volume 83(10):1537-1544 October 1, 2001 ©2001 by The Journal of Bone and Joint Surgery, Inc.

2 Correlation between the extent of ossification of the posterior longitudinal ligament (OPLL extent) and each of the other factors—age (A), body-mass index (BMI) (B), fasting plasma glucose level (FPG) (C), hemoglobin A1c level (Hb A1c) (D), fasting serum in... Toru Akune et al. J Bone Joint Surg Am 2001;83:1537-1544 ©2001 by The Journal of Bone and Joint Surgery, Inc.

3 Correlation between the extent of ossification of the posterior longitudinal ligament (OPLL extent) and each of the other factors—age (A), body-mass index (BMI) (B), fasting plasma glucose level (FPG) (C), hemoglobin A1c level (HB A1c) (D), fasting serum in... Toru Akune et al. J Bone Joint Surg Am 2001;83:1537-1544 ©2001 by The Journal of Bone and Joint Surgery, Inc.

4 Correlation of the extent of ossification of the posterior longitudinal ligament (OPLL extent) and insulinogenic index with each stage of glucose tolerance—normal glucose tolerance (NGT), impaired glucose regulation (IGR), and diabetes mellitus (DM)—in the... Toru Akune et al. J Bone Joint Surg Am 2001;83:1537-1544 ©2001 by The Journal of Bone and Joint Surgery, Inc.

5 The mean values for the extent of ossification of the posterior longitudinal ligament (OPLL extent) in patients with each genotype of insulin receptor substrate-1 (IRS-1) polymorphism. Toru Akune et al. J Bone Joint Surg Am 2001;83:1537-1544 ©2001 by The Journal of Bone and Joint Surgery, Inc.

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