1. Cell Cycle and Mitosis Organization of the process of cell division!

2. Do all cells divide? Divide –Stem Cells –Glial cells in the brain –Skin cells –Cancer cells Senescence –Red Blood Cells –Neurons –Cardiac

3. Why might a cell need to divide? Embryonic Development Repair Tissues Cells have a max surface area to volume ratio Asexual reproduction Cancer

4. Types of Cell Division Binary Fission –Prokaryotic Cell Division Mitosis –Eukaryotic Cell Division Meiosis –Production of sex cells

5. What is the meaning of mitosis? Interphase Mitosis Cytokinesis

6. Organization of Genetic Material: Chromatin vs. Chromosome

7. How does the cell change during the cell cycle? Are the stages discreet or continuous? What is important about metaphase?

8. What tells a cell to divide? External Controls –Growth Factors Internal Controls –Cyclins –CDK

9. Cell Cycle in Eukaryotes

10. How does cyclin ’ s struture allow for its function of promoting mitosis?

11. What proteins control cell growth internally? CDK: always present in cells Cyclin: level varies throughout the cell cycle MPF: “ mitosis promoting factor ” --occurs when cyclin binds to CDK.

12. Control of Cell Cycle Animation Cell cycle is Nobel Prize work! Animation www.nobelprize.org/ educational/medicine/ 2001 Choose: Control of Cell Cycle Around your cell cycle picture, add additional information that you learned including the role of energy!

13. Cancer Cancer is when the cell cycle goes wrong. What might happen to cause a cell cycle to wreak havoc?