Download presentation
Presentation is loading. Please wait.
Published byMelinda Neal Modified over 9 years ago
1
Glycolysis Eric Niederhoffer SIU-SOM Glucose Pyruvate Lactate 10 steps No O 2 Energy (ATP) and metabolites 3 regulated steps
2
Pathway Overview n What does glycolysis do for us? Process Glc (Frc) monomers Form 3-C metabolites Generate ATP and NADH Input to Glycogen, PPP TCA PPP Glycogen ATP NADH Glc G6P F6P F16BP DHAP +G3P 1,3-BPG 3-PG 2-PG PEP Pyr Input to TCA cycle Lactate PGK PK (reg) G3P DH LDH HK (reg) PFK-1 (reg) Regenerate NAD +
3
Regulation Glc G6P F6P F16BP DHAP +G3P 1,3-BPG 3-PG 2-PG PEP Pyr PK HK PFK-1 Epinephrine (cardiac muscle) cAMP ATP F26BP PFK-2 (active) PFK-2 (inactive) AC PKA (active) PKA (inactive)
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.