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Published byJocelyn Casey Modified over 8 years ago
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Cracking the NRPS Code Nick Till Computational Biology 12-15-2015
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Proteins without Genes Tyrocidine Vancomycin
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Nonribosomal Peptide Synthesis Taken without permission from J. Christopher Anderson
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A-domain Recognition Site Chem. And Biol. 1999, 6, 493-505
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A-domain Sequences
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Machine Learning Approach
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Information Content in 10-mers
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Prediction Results
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Conclusion Predictor works for about 50% of sequences picked at random IC Bar Charts show some explanation for some poor predictions A more intricate weighting function for the Hamming Distance could improve prediction power.
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Signatures Chem. And Biol. 1999, 6, 493-505
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