1. Pacemakers and AICD ’ s

2. Pacemaker Basics Provides electrical stimuli to cause cardiac contraction when intrinsic cardiac activity is inappropriately slow or absent Sense intrinsic cardiac electric potentials

3. ICD Basics Designed to treat a cardiac tachydysrythmia Performs cardioversion/defibrillation Ventricular rate exceeds programmed cut-off rate Ventricular rate exceeds programmed cut-off rate ATP (antitachycardia pacing) Overdrive pacing in an attempt to terminate ventricular tachycardias Overdrive pacing in an attempt to terminate ventricular tachycardias Some have pacemaker function (combo devices)

5. Pacemaker and ICD Basics Pulse Generators Placed subcutaneously or submuscularly Placed subcutaneously or submuscularly Connected to leads Connected to leads Battery Battery Most commonly lithium-iodide type Life span 5 to 8 years Output voltage decreases gradually Makes sudden battery failure unlikely Makes sudden battery failure unlikely

6. Pacemaker and ICD Basics Asynchronous Fixed rate Fixed rate Impulse produced at a set rate Impulse produced at a set rate No relation to patients intrinsic cardiac activity No relation to patients intrinsic cardiac activity Susceptible to Torsades if impulse coincides with t wave Susceptible to Torsades if impulse coincides with t wave

7. Pacemaker and ICD Basics Synchronous Demand mode Demand mode Sensing circuit searches for intrinsic depolarization potential Sensing circuit searches for intrinsic depolarization potential If absent, a pacing response is generated If absent, a pacing response is generated Can mimic intrinsic electrical activity pattern of the heart Can mimic intrinsic electrical activity pattern of the heart

8. Pacemaker Nomenclature IIIIIIIVV Chamber Paced Chamber Sensed Response to Sensing Rate Modulation, Programmability Anti- tachycardia Features A=AtriumA=AtriumT=TriggeredP=SimpleP=Pacing V=VentricleV=VentricleI=Inhibited M=Multi- programmable S=Shock D=DualD=DualD=Dual R=Rate Adaptive D=Dual O=NoneO=NoneO=NoneC=Communicating O=None

9. Examples VVI Paces ventricle Paces ventricle Senses ventricle Senses ventricle Inhibited by a sensed ventricular event Inhibited by a sensed ventricular event

10. Pacing Nomenclature Examples AAT Paces atria Paces atria Senses atria Senses atria Triggers generator to fire if atria sensed Triggers generator to fire if atria sensedDDD Paces atria and ventricle Paces atria and ventricle Senses atria and ventricle Senses atria and ventricle Atrial triggered and ventricular inhibited Atrial triggered and ventricular inhibited EKG – 2 spikes EKG – 2 spikes

11. Atrial Spike Ventricular Spike DDD

12. Pacemaker Lead System Endocardial leads placed via central access Placed in right ventricle and/or atria Placed in right ventricle and/or atria Fixed to the endocardium via screws or tines Experimental pacing systems 2 atrial leads (minimize afib) 2 atrial leads (minimize afib) Biventricular pacing Biventricular pacing

15. Magnet Inhibition Closes an internal reed switch Causes sensing to be inhibited Causes sensing to be inhibited Temporarily turns pacemaker into “ asynchronous ” mode (set rate) Temporarily turns pacemaker into “ asynchronous ” mode (set rate) Does NOT turn pacemaker off Rate can confer info regarding battery life Distinct rates for BOL, ERI, EOL Distinct rates for BOL, ERI, EOL

16. Pacemaker Indications Absolute indications Sick sinus syndrome Sick sinus syndrome Symptomatic sinus bradycardia Symptomatic sinus bradycardia Tachy-brady syndrome Tachy-brady syndrome Afib with slow ventricular response Afib with slow ventricular response 3 rd degree heart block 3 rd degree heart block Chronotropic incompetence Chronotropic incompetence Inability to increase heart rate to match exercise Prolonged QT syndrome Prolonged QT syndrome

17. Pacemaker Indications 3 rd Degree heart block

18. Pacemaker Indications Relative indications Cardiomyopathy CardiomyopathyDilatedHypertrophic Severe refractory neurocardiogenic syncope Severe refractory neurocardiogenic syncope Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation

19. ICD Indications Generally Used in cases where there was a previous cardiac arrest Used in cases where there was a previous cardiac arrest Or, patients with undetermined origin or continued VT or VF despite medical interventions Or, patients with undetermined origin or continued VT or VF despite medical interventions

20. Pacemaker Complications EKG abnormalities due to Failure to output Failure to output Failure to capture Failure to capture Sensing abnormalities Sensing abnormalities Operative failures Operative failures

21. Pacemaker Failure to Output Definition No pacing spike present despite indication to pace No pacing spike present despite indication to paceEtiology Battery failure, lead fracture, break in lead insulation, oversensing, poor lead connection, “ cross-talk ” Battery failure, lead fracture, break in lead insulation, oversensing, poor lead connection, “ cross-talk ” Atrial output is sensed by ventricular lead

22. Pacemaker Failure to Capture Definition Pacing spike is not followed by either an atrial or ventricular complex Pacing spike is not followed by either an atrial or ventricular complexEtiology Lead fracture or dislodgement, break in lead insulation, elevated pacing threshold, MI at lead tip, drugs, metabolic abnormalities, cardiac perforation, poor lead connection Lead fracture or dislodgement, break in lead insulation, elevated pacing threshold, MI at lead tip, drugs, metabolic abnormalities, cardiac perforation, poor lead connection

23. Pacemaker Sensing Abnormalities Oversensing Senses noncardiac electrical activity and is inhibited from correctly pacing Senses noncardiac electrical activity and is inhibited from correctly pacing Etiology Etiology Muscular activity (diaphragm or pecs), EMI, cell phone held within 10cm of pulse generator Undersensing Incorrectly misses intrinsic depolarization and paces Incorrectly misses intrinsic depolarization and paces Etiology Etiology Poor lead positioning, lead dislodgement, magnet application, low battery states, MI

24. Pacemaker Operative Failures Due to pacemaker placement Pneumothorax Pneumothorax Pericarditis Pericarditis Perforated atrium or ventricle Perforated atrium or ventricle Dislodgement of leads Dislodgement of leads Infection or erosion of pacemaker pocket Infection or erosion of pacemaker pocket Infective endocarditis (rare) Infective endocarditis (rare) Venous thrombosis Venous thrombosis

25. Pacemaker Complications Pacemaker syndrome Patient feels worse after pacemaker placement Patient feels worse after pacemaker placement Presents with progressive worsening of CHF symptoms Presents with progressive worsening of CHF symptoms Due to loss of atrioventricular synchrony, pathway now reversed and ventricular origin of beat Due to loss of atrioventricular synchrony, pathway now reversed and ventricular origin of beat

26. ICD Complications Similar to pacemaker complications Operative failures Operative failures Same as pacemakers Sensing and pacing failures Sensing and pacing failures Inappropriate cardioversion Inappropriate cardioversion Ineffective cardioversion/defibrillation Ineffective cardioversion/defibrillation Device deactivation Device deactivation

27. ICD Sensing failures Similar to pacmakers Oversensing Oversensing Undersensing Undersensing Appropriate failure to treat Programmed cut off at 180 bpm Programmed cut off at 180 bpm If V Tach occurs at 160 bpms, appropriately fails to cardiovert If V Tach occurs at 160 bpms, appropriately fails to cardiovert

28. ICD Inappropriate Cardioversion Most frequent complications Provokes pain and anxiety in pts Consider when Pt is in afib Pt is in afib With ventricular response > programmed cut off Received multiple shocks in rapid succession Received multiple shocks in rapid successionEtiology Afib, T-wave oversensing, lead fracture, insulation breakage, MRI, EMI Afib, T-wave oversensing, lead fracture, insulation breakage, MRI, EMI

29. ICD Inappropriate Cardioversion Treatment Magnet over ICD inhibits further shocks Magnet over ICD inhibits further shocks Does NOT inhibit bradycardiac pacing Does NOT inhibit bradycardiac pacingNote Some older devices produce beep with each QRS Some older devices produce beep with each QRS If left on for >30 seconds, ICD disabled and continous beep If left on for >30 seconds, ICD disabled and continous beep To reactivate, lift off magnet and then replace for > 30 seconds, beep will return with each QRS To reactivate, lift off magnet and then replace for > 30 seconds, beep will return with each QRS

30. ICD Failure to Deliver Cardioversion Etiology Failure to sense, lead fracture, EMI, inadvertent ICD deactivation Failure to sense, lead fracture, EMI, inadvertent ICD deactivationManagement External defibrillation and cardioversion External defibrillation and cardioversion Do not withhold therapy for fear of damaging ICD If pt ’ s internal defibrillator activates during chest compressions, you may feel a mild shock (no reports of deaths related to this) Antidysrhymthic medications Antidysrhymthic medications

31. ICD Ineffective Cardioversion Etiology Inadequate energy output Inadequate energy output Rise in the defibrillation threshold Rise in the defibrillation threshold MI at the lead site MI at the lead site Lead fracture Lead fracture Insulation breakage Insulation breakage Pre-programmed set of therapies per dysrythmia Manufacturer specific Manufacturer specific Once number of attempts reached, will not deliver further shocks until new episode is declared Once number of attempts reached, will not deliver further shocks until new episode is declared

32. Electromagnetic Interference Can interfere with function of pacemaker or ICD Device misinterprets the EMI causing Rate alteration Rate alteration Sensing abnormalities Sensing abnormalities Asynchronous pacing Asynchronous pacing Noise reversion Noise reversion Reprogramming Reprogramming

33. Electromagnetic Interference Examples Metal detectors Metal detectors Cell phones Cell phones High voltage power lines High voltage power lines Some home appliances (microwave) Some home appliances (microwave)

34. Electromagnetic Interference Intensity of electromagnetic field decreases inversely with the square of the distance from the source Newer pacemakers and ICDs are being built with increased internal shielding