1. Yellow fever
Chelsea Booth

2. What is yellow fever? Mosquito virus
Tropical/subtropical South America and Africa
Spread via slave trade

4. Transmission RNA virus, Flavivirus genus
Through the bite of the infected Aedes or Haemagogus species
Mosquitos get infected from the blood of infected primates
3 cycles
Jungle (Sylvatic): monkeys to mosquitos to humans working in the jungle
Savannah: monkey to human or human to humans working in the jungle
Urban: human to human via mosquito

7. symptoms
Many cases present no symptoms Incubation period 3-6 days Sudden onset fever, chills, headache, back pain, general body aches, nausea, vomiting, fatigue, weakness. General improvement follows 15% cases more severe. High fever, jaundice, bleeding, shock and organ failure

8. Diagnosis & treatment
Use combination of symptoms, travel history Blood test for anti-YFV antibodies where available Treat symptoms. Rest, fluid and pain medication/fever reducer NSAIDS increase risk of bleeding Take care infected people aren’t bit by mosquitos during this time to prevent spread of virus

9. prevention
Insect repellent Protective clothing Staying indoors / air conditioning Vaccination older than 9 months, traveling to at risk area no longer need a booster immunocompromised should not be vaccinated some nations require proof of vaccination

11. Yellow fever: the numbers
1 billion people live in area where disease is common
Cases increasing because: fewer immune, cities, movement, climate change
200,000 infections/30,000 deaths per year
90% in Africa

15. References
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