1. Speed, Ice & Madness A biology teacher’s guide to the stimulants in 2006 Dr Edward Ogden PSM MA MBBS BMedSc GradCertMgt FRACGP FAChAM

2. NIDA’s mission is to bring the power of science to bear on drug abuse and addiction.

3. Prevalence World wide use estimated 0.6% of population Australia has highest prevalence in the world! 9.1 % used at some stage 3.2% used the previous 12 months. Average age at first use 20.8 years. 6.6% of Australian teenagers have had experience with amphetamines 97% if IDU’s have tried stimulants

4. Why worry? Users little understanding of effects of drug High risk of HIV and STD High rate of conversion from oral to IV Unlikely to seek help Toxicity 25% of users are psychotic 20% of psychoses longer than 1 month

5. A little neuropsychology!

10. Addictions & the reward pathway Food Water Sex Nurturing

14. The action of stimulants Amphetamine-type Stimulants Cocaine

28. www.drugabuse.gov Positron Emission Tomography

29. www.drugabuse.gov NormalOn Cocaine

30. 1-2 Min3-45-6 6-77-8 8-9 9-1010-20 20-30 Brain on Cocaine Cocaine binding

31. A Brain After Cocaine Metabolic Activity

32. Long-term Consequences Metabolic Activity

33. The Memory of Drugs Nature Video Cocaine Video Amygdala not lit up Amygdala activated

34. The good news is… Drug Abuse is a preventable behavior and Drug Addiction is a treatable disease

35. … Is it worth the risk?

36. For More Information NIDA Public Information Office: 301-443-1124Or www.nida.nih.gov www.drugabuse.gov National Clearinghouse on Alcohol and Drug Information (NCADI): 1-800-729-6686 www.drugabuse.gov

37. Have you changed your mind?