1. JUST DISORDERS

2. What disorder is it? Mutation in the blood clotting protein makes person unable to stop bleeding after an injury _______________ Mutation in hemoglobin causes red blood cells to change shape and ____________________ clog up blood vessels Mutation causes mental retardation if foods containing phenylalanine are eaten _____________________ Three #21 chromosomes are present causing mental retardation _______________________ Mutation in ion channel protein causes thick mucous to clog up lungs and digestive organs _______________________ Hemophilia Sickle cell anemia Phenylketonuria (PKU) Down syndrome Cystic fibrosis

3. What disorder is it? Gradual deterioration of the brain that appears during middle age resulting in nursing home care and early death ____________________ Progressive weakening of muscle proteins resulting in inability to walk and eventually death_________________________ Inability to distinguish between the colors red and green _____________________ Only one X and no y chromosome ____________________ resulting in infertility Huntington’s disease (HD) Duchenne Muscular dystrophy Colorblindness Turner syndrome

4. What disorder is it? Twins that are born joined together ____________________ Males with an extra X chromosome ______________________ (XXY) karyotype; some female features; infertility Pattern of hair loss in which _____________________ homozygous persons(male& female) & heterozygous males lose their hair in a predictable pattern Failure of the bone and skin to grow correctly and cover the spinal cord __________________________ Conjoined twins Kleinfelter syndrome Male pattern baldness Spina bifida

5. Dominant/recessive? Autosomal/X-linked/nondisjunction Turner syndrome ____________________ Cystic fibrosis ____________________ Hemophilia _____________________ Colorblindness __________________ Phenylketonuria ___________________ Duchenne muscular dystrophy ________________ Nondisjunction Autosomal recessive X-linked recessive Autosomal recessive X-linked recessive

6. Dominant/recessive? Autosomal/X-linked/nondisjunction Phenylketonuria ____________________ Down syndrome ____________________ Sickle cell anemia _____________________ Kleinfelter syndrome ____________________ Huntington’s disease ______________________ Male pattern baldness _________________ Autosomal recessive nondisjunction Autosomal recessive nondisjunction Autosomal dominant

7. Name 3 disorders that are: Autosomal recessiveX linked recessive ______________________________ _______________________________ Phenylketonuria (PKU) Sickle cell anemia Cystic fibrosis Others in book: Tay Sach’s Albinism Hemophilia Colorblindness Duchenne Muscular dystrophy Others in book: Achondroplasia (dwarfism) Polydactyly (extra fingers/toes)

8. Name a SEX INFLUENCED TRAIT _____________________ Male pattern baldness Name 3 disorders that is caused by nondisjunction: ___________________ Down syndrome Turner syndrome Kleinfelter syndrome XXX Xyy

9. Name a POLYGENIC TRAIT _____________________ Human height Intelligence Eye color Hair color Name a multiple allele trait: __________________ A, B, O blood type