1. Conference-Cum-Awareness Program on Quality Management in Pharmaceutical Manufacturing Dr. B.B. Rai MBBS, MD (PSM) Executive Director VHAS, Tadong-Gangtok Date: 28 th January 2016 Venue: Hotel Rendezvous, Gangtok

2. SIKKIM STATE: 1. Sikkim: India’s least populous state 2. Located in North East 3. Boundaries with China, Bhutan, Nepal 4. Second smallest state in India 5. Total Area : 7,096 Sq. Kms 6. Mountainous, landlocked state

3. 1. Total population: 6,10577 2. Infant Mortality Rate: 24 3. Death Rate: 5.6 4. Birth Rate: 17.6 5. Sex Ratio: 889 F per 1000 M 6. Literacy Rate: M: 87 % F: 76 %

4. Education: 1. Total Government Schools:781 2. Total Private Schools: 421 3. Total Monastic Schools: 71 4. Total Local Body Schools: 25 5. Total Sanskrit Schools: 11 6. Total Islamic Schools: 03 There are other institutions and Universities imparting education in the state

5. Health: Health care services is provided almost entirely by the public sector 1. District Hospital: 04 2. PHCs: 24 3. Sub Centres: 147 4. STNM Hospital 5. Sikkim Manipal Central Referral Hospital Health care is provided by 273 doctors and 09 AYUSH practitioners (HRD 2014)

6. Doctors Ratio:1 : 2500 (Approx.) Beds Ratio:2.6 : 1000 (Approx.) STNM Hospital : 1. Established in 1917, nearing centuries 2. Total beds: 330 3. Catering out-patients every year : 4.00 lakhs (approx.) 4. Catering in-patients every year : 45 thousand

7. 1. Maternal Death : 25 (2011-12) ; 19 (2012-13) 2. Infant Mortality Rate : 24 3. U5 Mortality Rate : 40 4. The Prevalence of HIV amongst pregnant women : 0.15 % 5. Total VIV/AIDS Cases registered: 361 6. AIDS patients death : 37 person during 2006-9 7. Malaria prevalence rate : 0.27 % per 1000 8. RNTCP started : 01 st March 2002 9. Total TB units : 05 10. Total 1646 cases reported (June 2010) out of which 37 had died (Mortality rate: 2.24 %)

8. 1. Sikkim has attracted significant investments from Pharmaceutical companies over last five years 2. More than 10 pharmaceutical companies (15) 3. Investments upwards of Rs. 25,000 million Advantages: 1. 100 % excise duty exemption on finished products manufactured 2. 100 % exemption on income tax 3. 30 % subsidy on the investment of plant & machinery (Capital investment) 4. 3 % subsidy on working capital loan 5. Reimbursement of 100 % insurance premium

9. 1. Maternal Deaths 2. Infants Deaths 3. Tuberculosis 4. Cancers 5. Suicides 6. Substance abuse 7. Other Non-Communicable Diseases

10. Partnership Community Program Pharma Companies NGOs/Civil Societies Government

11.  Thanks