1. Cognitive Research & NCMRR Michael Weinrich, M.D. Director, National Center for Medical Rehabilitation Research NICHD, NIH Bethesda, MD mw287K@nih.gov

2. NCMRR Established 1990 PL 101-613 Center within NICHD Advisory Board Research Plan 1993 Rehab Coordinating Committee Funds research, training & SBIR

3. NCMRR Systems Approach Patho- physiology Impairment Functional Limitation Disability Societal Limitation

4. Research Plan: Areas of Emphasis Mobility Behavioral Adaptation Whole Body Response Assistive Technologies Measurement, Assessment & Epidemiology Treatment Effectiveness Training Rehabilitation Scientists

5. October 1998 http://www.nichd.nih.gov/public ations/pubs/traumatic/Abstracts. htm http://odp.od.nih.gov/consensus/ cons/109/109_statement.htm

6. AHCPR Evidence-Based Practice Report 1.Should interdisciplinary rehabilitation begin during acute hospitalization for TBI? 2.Does the intensity of inpatient interdisciplinary rehabilitation affect long-term outcomes? 3.Does the application of cognitive rehabilitation enhance outcomes for persons who sustain TBI? 4.Does the application of supportive employment enhance outcomes for persons with TBI? 5.Does the provision of long-term care coordination enhance the general functional status of persons with TBI?

7. Needs in Cognitive Rehabilitation Research Establish and evidence base for clinical practice Incorporate knowledge from experimental psychology: errorless learning, imagery, etc. Adopt new technologies: adaptive learning, VR, multi-modal presentation, cueing strategies, etc.

8. Range of Current Research on Cognition Supported by NCMRR Cognitive Rehabilitation for TBI “Talking Lights” fMRI & EP especially in recovery VR and driving Rehabilitation of cognitive symptoms in MS Cognitive rehabilitation--acquired dyslexia Problem solving in acquired brain damage

9. RFA: RFA-HD-01-007 COOPERATIVE MULTICENTER TRAUMATIC BRAIN INJURY CLINICAL TRIALS NETWORK Release Date: March 26, 2001

10. RFA: HD-00-016 INNOVATIVE REHABILITATION INTERVENTIONS Release Date: June 27, 2000 54 Applications received

11. CLINICAL TRIAL PLANNING GRANTS TO GUIDE TIMING, INTENSITY, AND DURATION OF REHABILITATION FOR STROKE AND HIP FRACTURE Release Date: September 20, 2001 RFA: RFA-HD-01-022 Letter of Intent Receipt Date: January 18, 2002 Application Receipt Date: February 14, 2002

12. ALTERNATIVE AND ALTERNATIVE COMMUNICATION STRATEGIES FOR TREATMENT OF COGNITIVE-LINGUISTIC DISORDERS Letter of Intent Receipt Date: February 2002 (30 days prior to submission date) Application Receipt Date:March 2002

13. NCMRR Behavioral Sciences and Rehabilitation Engineering (SBIR) Biological Sciences and Career Development Clinical Practices Program Lou Quatrano, PhD 301-402-4221 lq2n@nih.gov Ralph Nitkin, PhD 301-402-4206 rn21e@nih.gov Beth Ansel, PhD 301-496-5289 anselb@mail.nih.gov