1. Urinary system

2. Compounds and functions
Embryogenesis
Kidney
Nephrons types
Blood supplying
Glomerular filter
Nephrons histophysiology
Endocrine system of kidney
Urine transport system

3. Kidneys function –. urine production. endocrine Ureters –
Kidneys function – urine production endocrine Ureters – voiding of urine Urinary bladder – urine deposition Urethra – voiding of urine

4. Embryogenesis of urinary system
Source – intermediate mesoderm (nephrogonotom)
Stages – pronephroi
mesonephroi
metanephroi

5. Kidney

6. MFU – nephron renal corpuscle+tubular system Types: 1
MFU – nephron renal corpuscle+tubular system Types: 1. cortical – short and long 2. juxtamedullary

7. Blood supply
25% of cardiac output
Two capillary systems (glomerular and peritubular)
High blood pressure in glomerulus

9. Vascularization of nephrones

10. Vascularization of nephrones

11. Renal cortex

12. Renal corpuscle

13. Between circulating blood and urinary space
Glomerular filter
Between circulating blood and urinary space
Podocyte
Basement membrane unusialy thick physical and electrical barrier
Endothelium fenestrated

14. Glomerular filter

15. Renal corpuscle ultrastructure

16. Proximal convoluted tube

17. Proximal convoluted tube

18. Distant convoluted tube

19. Distant convoluted tube

20. Urine production Stage Place Mechanism Filtration High blood pressure
Renal corpuscle
High blood pressure
reabsorption
Tubules
Active – by cells
Passive – onkotic pressure
Secretion
Collecting tube H+

22. Urine production

23. Endocrine system of kidneys
Renin-angiotensin
Prostaglandins
Callicrein-kinins
Erythropoietin
Juxtaglomerular apparatus
Juxtaglomerular cells – afferent arteriol – renin secretion
Juxtavascular cells (Hurmating’s cells) – with process – triogonal place
Macula densa area – distant canal – Na receptor
Mesangial cells - renin and erythropoetin secretion

25. Macula densa

28. Urine transport system
Renal pelvis
Ureters
Urinary bladder
Urethra
Tunics
I Mucosa: epithelium (urothelium)
lamina propria
muscularis mucosa
II Submucosa
III Muscular
IV Adventitia

29. ureter

30. ureter

31. Urinary blader