1. Complex Patterns of Inheritance
Ch 11

2. Exceptions to Mendelian Genetics
Summary
Exceptions to Mendelian Genetics
Polygenic
Incomplete Dominance
Co-Dominance
Multiple Alleles
Pleiotropy
Gene linkage
Sex-linked Traits
OTHER Extension:
Karyotype
Pedigrees
Patterns of inheritance
Inferring genotype
Non-disjunction - trisomy

4. Where is this happening again?

5. Poly-genic Traits

6. Complete Dominance

9. Different?

16. Multiple Alleles

17. glycoproteins = antigens
A B – Codominance / multiple alleles
I or i = do not make A or B
A, B > i dominance
A=B  Codominant
Rh Factor = + or - ….another glycoprotein – present or absent
Genotypes (6) = Phenotypes (4)
AA, Ai = A
BB Bi = B
AB = AB
ii = O

18. Universal receptor (+)
Universal donor ( O -)

19. Compare and Contrast

20. Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits. Consequently, a mutation in a pleiotropicgene may have an effect on some or all traits simultaneously. Anexample is phenylketonuria, a human disease that affects multiple systems but is caused by one gene defect.
Pleiotropy: Cystic fibrosis is a good of example of pleiotropy, where a mutation in a single gene affects multiple systems in this case the lungs, pancreas, and sweat glands

22. BIO SmartStarter – 11/20/15 Xb - Color Blind XB – not Color Blind
1. Make a Punnett square for the cross illustrated here.
2. What are the genotypic and phenotypic ratios (probabilities) for the offspring?