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2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM.

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Presentation on theme: "2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM."— Presentation transcript:

1 2004-2005 Pharmacology Review of Everything (Principles, Cardiovascular and Respiratory drugs have been updated) 19 February 2016 2:39 PM

2 Spectinomycin Antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome

3 Spironolactone Potassium sparing diuretic Antiandrogen Aldosterone receptor antagonist Androgen receptor antagonist Testosterone synthesis inhibitor Antihypertensive Heart failure treatment

4 St. John’s Wort Dietary supplement Antidepressant

5 Streptokinase Thrombolytic

6 Streptomycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

7 Succinylcholine Paralytic Depolarizing blocker Paralyzes skeletal muscles Bronchoconstrictor

8 Sucralfate Antiulcer

9 Sufentanil Opioid General anaesthetic Intravenous anaesthetic

10 Sulfacetamide Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase Topical

11 Sulfadoxine Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Dihydropteroate synthetase inhibitor

12 Sulfamethoxazole Sulfonamide antibiotic Microbial nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

13 Sulfasalazine Disease modifying anti-rheumatic drug (DMARD) Metabolized to sulfonamide + salicylate (NSAID) Treatment of IBD

14 Sulfinpyrazone Uricosuric Anti-gout

15 Sulfisoxazole Sulfonamide antibiotic Nucleic acid and protein synthesis inhibitor Inhibits dihydropteroate synthetase

16 Sulfonamides Antibiotics Nucleic acid and protein synthesis inhibitors Inhibit dihydropteroate synthetase

17 Sulindac NSAID Analgesic, Anti-inflammatory, Antipyretic Cyclooxygenase inhibitor

18 Suramin Tropical antiparasitic Treatment of African Trypanosomiasis

19 Tacrolimus Immunosuppressive Antineoplastic Binds FKBP (FK506 binding protein) Inhibits calcineurin

20 Tamoxifen Antineoplastic Antiestrogen Estrogen receptor anatagonist

21 Tegaserod IBS treatment 5HT 4 receptor agonist

22 Telmisartan Antihypertensive Angiotensin receptor blocker (ARB)

23 Temazepam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

24 Tenecteplase Thrombolytic Tissue plasminogen activator (tPA)

25 Terazosin Sympatholytic  1 adrenergic antagonist Antihypertensive Treatment for benign prostatic hypertrophy

26 Terbinafine Allylamine antifungal Inhibits ergosterol synthesis by inhibiting squalene epoxidase

27 Terbutaline Sympathomimetic  2 adrenergic agonist Short acting bronchodilator Tocolytic Uterine relaxant

28 Testosterone Androgen Natural male gonadal steroid

29 Testosterone cypionate Androgen Synthetic depot

30 Testosterone enanthate Androgen Synthetic depot

31 Testosterone propionate Androgen Synthetic depot

32 Tetracaine Local anaesthetic

33 Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment

34 Thalidomide Antineoplastic Leprosy treatment Anti-angiogenic Anti-TNF 

35 Theophylline Bronchodilator Methylxanthine Phosphodiesterase inhibitor Used in asthma

36 Thiabendazole Antihelminthic Treatment of intestinal roundworms

37 6-Thioguanine Antineoplastic Antimetabolite (“pseudofeedback inhibition” of HGPRT and PRP – purine synthesis)

38 Thiopental General Anaesthetic Ultra-short-acting barbiturate

39 Thioridazine Antipsychotic Phenothiazine

40 Thiotepa Antineoplastic Alkylating agent

41 Thiothixene Antipsychotic

42 Thrombopoietin Cytokine Platelet synthesis stimulator

43 Thromboxane A 2 (TXA 2 ) Autacoid Promotes platelet aggregation Cyclooxygenase product of arachidonate metabolism

44 Thyrotropin-releasing Hormone (TRH) Hypothalamic hormone Stimulates release of thyroid stimulating hormone (TSH) from the anterior pituitary

45 Thyrotropin Thyroid-stimulating Hormone (TSH) Anterior pituitary hormone Stimulates production of thyroxine (T 4 ), triiodothyronine (T 3 ) and thyroglobulin

46 Ticarcillin Penicillin antibiotic Cell wall synthesis inhibitor Anti-pseudomonal penicillin Inhibits peptidoglycan cross-linking

47 Ticlopidine Antiplatelet ADP receptor antagonist

48 Timolol Sympatholytic  adrenergic antagonist Antihypertensive Glaucoma treatment Anti-anginal Bronchoconstrictor

49 Tissue plasminogen activators Thrombolytics alteplase, reteplase, tenecteplase

50 Tobramycin Aminoglycoside antibiotic Bactericidal protein synthesis inhibitor 30S ribosome Freezes initiation

51 Tocainide Class I antiarrhythmic Na + channel blocker (activated channels)

52 Tolbutamide Oral hypoglycemic Sulfonylurea Insulinotropic

53 Tolterodine Anticholinergic Muscarinic receptor antagonist Prevents urination

54 Toremifene Estrogen antagonist Selective estrogen receptor modulator (SERM)

55 Tosemide Loop diuretic Na-K-2Cl symporter inhibitor

56 Trandopril Antihypertensive Converting enzyme inhibitor

57 Tranylcypromine Antidepressant Monoamine oxidase inhibitor (MAO-I)

58 Trastuzumab Antineoplastic Anti-HER2 antibody

59 Triamcinolone Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled

60 Triamterene Potassium sparing diuretic Sodium channel inhibitor Antihypertensive

61 Triazolam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

62 Trifluoperazine Antipsychotic Phenothiazine

63 Trifluridine Antiherpes Pyrimidine analog Phosphorylated to inhibitor of viral DNA polymerase

64 Trihexyphenidyl Antiparkinson Antimuscarinic

65 Trimethaphan Sympatholytic Anticholinergic Nicotinic antagonist Antihypertensive

66 Trimethoprim Antibiotic Protein and nucleic acid synthesis inhibitor Inhibits bacterial dihydrofolate reductase

67 Tripelennamine Classical antihistamine H 1 antagonist

68 Tubocurarine Paralytic Paralyzes skeletal muscles

69 Tumor necrosis factor  Cytokine Antineoplastic

70 Tyramine Indirect sympathomimetic Vasoconstrictor Vasopressor

71 Ultralente insulin Hormone Insulin analogue Long acting

72 Urokinase Thrombolytic

73 Valacyclovir Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase

74 Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

75 Valganciclovir Antiherpes Purine analog Phosphorylated to inhibitor of viral DNA polymerase

76 Valproic acid Anticonvulsant

77 Valsartan Antihypertensive Angiotensin receptor blocker (ARB)

78 Vancomycin Antibiotic Inhibits cell wall synthesis Not a  lactam

79 Arginine vasopressin (Antidiuretic hormone; ADH) Hypothalamic (posterior pituitary) hormone Antidiuretic Vasoconstrictor

80 Vecuronium Paralytic Paralyze skeletal muscles

81 Verapamil Class IV antiarrhythmic Antihypertensive L-type Ca 2+ channel blocker Antianginal

82 Vigabatrin Anticonvulsant Irreversible GABA aminotransferase inhibitor

83 Vinblastine Antineoplastic Vinca alkaloid Natural product

84 Vincristine Antineoplastic Vinca alkaloid Natural product

85 Voriconazole Triazole antifungal Inhibits synthesis of ergosterol by inhibiting lanosterol 14  demethylase

86 Warfarin Anticoagulant Vitamin K synthesis inhibitor

87 Zafirlukast Leukotriene inhibitor LTR 1 and LTD 4 antagonist Asthma treatment

88 Zalcitabine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Dideoxycytidine (ddC)

89 Zanamivir Antiviral Inhibits neuraminidase and decreases viral release Treatment of Influenza A & B

90 Zidovudine Antiretroviral Nucleoside reverse transcriptase inhibitor (NRTI) Azidothymidine (AZT)

91 Zileuton Leukotriene inhibitor 5-lipoxygenase inhibitor Used in asthma

92 Zolpidem Sedative/Hypnotic Non-benzodiazepine


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