1. Biomedical engineering

2. Objectives Check 210.T/E.4 Present research on current bioengineering technologies that advance health and contribute to improvements in our daily lives. SPI 3210.T/E.3 Evaluate the overall benefit to cost ratio of a new technology CLE 3210.4.7 Assess the scientific and ethical ramifications of emerging genetic technology

3. Engineering Design http://www.nasa.gov/audience/foreducators/plantgrowth/reference/Eng_Design_5-12.html

4. Challenge Question You are a newly married biomedical engineer. Both you and your spouse want to have children. However, you have discovered that both of you are carriers for the genetic disorder, Phenolketonuria, PKU. PKU is a disorder in which the body does not produce the enzyme phenylalanine hydroxylase. Without this enzyme, your body can not properly metabolize the amino acid phenylalanine. Build up of phenylalanine can cause multiple developmental issues including mental retardation. Worried that your children might inherit the disorder, you begin to research treatments and cures. You discover that the current treatment involves maintaining a strict diet low in phenyalanine. Though this treatment works, it is complicated to maintain the strict diet. As a biomedical engineer, you think that there has to be another option. Is there a way to cure this disorder? How might you engineer a product that change the course of this disorder for affected individuals?

5. Brainstorm: What are possible answers to the challenge question?

6. Things to think about in your brainstorming session (jot your answers down in your notebook) 1 What do you already know about this problem? 2. What do you need to know better to understand this problem? 3. Where might you look to find answers to the questions you develop?

7. Multiple Perspectives Related news from the experts

8. Click on the below link and answer the questions in your lab notebook Insulin article –http://www.med.uni- giessen.de/itr/history/inshist.htmlhttp://www.med.uni- giessen.de/itr/history/inshist.html Questions –What did you learn? –How does the article relate to the challenge question? –Revise question 3 from before: Where might you look to find answers to the questions you develop?

9. Research and Revise

10. Using what you have so far: Use the internet and research the problem and how you might be able to solve it!