1. Antiemetics & Antivertigo Drugs By : Glen Estrosos

2. Antiemetic Drugs Antiemetic drug is used to treat or prevent nausea or vomiting. Antiemetics are tipically used to treat motion sickness nd the side effects of opiod analgesics and chemotherapy directed against cancer. Examples:  Bucladin-Softabs  Thorazine

3. Structural Formula

4. Antivertigo Drugs Antivertigo drugs is used to treat vertigo, which is usually accompanied by lightheadedness, dizziness, and weakness. Examples:  Vontrol  Antivert

5. Actions These drugs appear to act primarily by inhibiting the CTZ (chemoreceptor trigger zone) or by depressing the sensitivity of the vestibular apparatus of the inner ear.

6. Actions cont. Those that act on the CTZ are more effective for vomiting caused by stimulation of the CTZ. Those that act on the vestibular apparatus of the inner ear are more effective for vertigo associated with motion sickness and middle and inner ear surgeries.

7. Side Effects Drowsiness Confusion Nausea & Vomiting

8. Adverse Reactions Drowsiness Confusion Dry mouth Headache Visual hallucinations Nausea Vomiting Restlessness Disorientation Sedation

9. Contraindications Antiametics and antivertigo drugs are contraindicated in the patients with hyper sensitivity to these drugs, those in coma, or those with severe CNS depression. These drugs are not recommended during pregnancy, lactation, or for uncomplicated vomiting in young children.

10. Interventions Dehydration is a serious concern in the patient experiencing nausea and vomiting. Observations for fluid and electrolyte imbalance. Observe I&O Avoid driving or performing other hazardous task when taking this drug.