1. Myocarditis: toward a better understanding for an improved diagnosis January 16 th, 2016 9h-10h30

2. A) A full recovery occurs in > 90% of cases B) 25% of patients will not recover a normal left ventricular systolic function C) Biventricular dysfunction at hospital entrance is associated with a poor clinical prognosis D) Ventricular rhythm disorder at hospital admission is associated with a poor clinical prognosis E) 12 to 25% of patients will have a non favourable evolution leading to death or severe dilated cardiomyopathy Which of the following proposition(s) about acute myocarditis is/are correct?

3. A) A full recovery occurs in > 90% of cases B) 25% of patients will not recover a normal left ventricular systolic function C) Biventricular dysfunction at hospital entrance is associated with a poor clinical prognosis D) Ventricular rhythm disorder at hospital admission is associated with a poor clinical prognosis E) 12 to 25% of patients will have a non favourable evolution leading to death or severe dilated cardiomyopathy Which of the following proposition(s) about acute myocarditis is/are correct? European Heart Journal (2013)34, 2636–2648

4. A)Virus serology are recommended as first line testing B)Circulating antibodies of IgG class against cardiotropic viruses are frequent in the general population C)There is a lack of correlation between serology and EMB (endomyocardial biopsy) D)Virus serology are indicated for immunodeficient patients Which of the following proposition(s) about acute myocarditis is/are correct?

5. A)Virus serology are recommended as first line testing B)Circulating antibodies of IgG class against cardiotropic viruses are frequent in the general population C)There is a lack of correlation between serology and EMB (endomyocardial biopsy) D)Virus serology are indicated for immunodeficient patients Which of the following proposition(s) about acute myocarditis is/are correct?

6. A) EMB sensibility for diagnosis of acute myocarditis is better a few weeks after patient’s admission B) EMB complications rate is low in experienced teams (0 to 0.8% of complications) C) If the EMB shows no sign of infection, it is possible to start immunosuppressive treatment D) HHV6-related myocarditis are most often very symptomatic E) In case of myocarditis presenting as SCA-like syndromes, the most common virus when present is Parvovirus B26 Which of the following proposition(s) about acute myocarditis is/are correct?

7. A) EMB sensibility for diagnosis of acute myocarditis is better a few weeks after patient’s admission B) EMB complications rate is low in experienced teams (0 to 0.8% of complications) C) If the EMB shows no sign of infection, it is possible to start immunosuppressive treatment D) HHV6-related myocarditis are most often very symptomatic E) In case of myocarditis presenting as SCA-like syndromes, the most common virus when present is Parvovirus B26 Which of the following proposition(s) about acute myocarditis is/are correct?

8. A) The diagnosis relies on the positivity of the 3 Louise Lake criteria B) Pericardial effusion is one of the Louise Lake criteria C) Hyperemia and capillary leak are seen on T2-weighted sequences. D) The White paper published in the JACC was a reference to the White Stripes singer E) Late gadolinium enhancement (LGE) is more specific than early enhancement Which of the following proposition(s) about MRI- related acute myocarditis diagnosis is/are correct?

9. A) The diagnosis relies on the positivity of the 3 Louise Lake criteria B) Pericardial effusion is one of the Louise Lake criteria C) Hyperemia and capillary leak are seen on T2-weighted sequences. D) The White paper published in the JACC was a reference to the White Stripes singer E) Late gadolinium enhancement (LGE) is more specific than early hyper enhancement Which of the following proposition(s) about MRI- related acute myocarditis diagnosis is/are correct?

10. A) Spectral CT scan has a low inter observer variability B) The exam duration is higher than with myocardial MRI C) Iodinated contrast medium is not required for the diagnosis D) The amount of iodinated contrast agent is not more than for coronary artery CT scan. E) There is a lack of correlation between positive LGE segments according to spectral CT scan and cardiac MRI. Which of the following proposition(s) about spectral CT scan and acute myocarditis diagnosis is/are correct?

11. A) Spectral CT scan has a low inter observer variability B) The exam duration is higher than with myocardial MRI C) Iodinated contrast medium is not required for the diagnosis D) The amount of iodinated contrast agent is not more than for coronary artery CT scan. E) There is a lack of correlation between positive LGE segments according to spectral CT scan and cardiac MRI. Which of the following proposition(s) about spectral CT scan and acute myocarditis diagnosis is/are correct?