1. The President’s Cancer Panel 2004/2005 Series Translating Research to Reduce the Burden of Cancer Margaret L. Kripke, Ph.D. January 25, 2005

2. The President’s Cancer Panel National Cancer Act of 1971 Oversees the National Cancer Program Three Members Meet Four Times per Year Reports to the President of the United States

3. Translating Research to Reduce the Burden of Cancer August 30, 2004–University of California at San Francisco September 27, 2004–The Ohio State University November 1, 2004–M.D. Anderson Cancer Center January 24, 2005–Memorial Sloan- Kettering Cancer Center

4. Laboratory Clinic Community

5. Laboratory to Clinic – Barriers Research culture Infrastructure Funding sources Conflict of interest Complexity of clinical trials

6. Research Culture Differing cultures of physicians and scientists Lack of incentives for team science Creation of knowledge vs. application Departmental structure

7. Infrastructure Access to human samples Interactive databases Conflict of interest Clinical trials support

8. Funding Sources Need for “gap” funding Demands on clinicians’ time Need for partnerships

9. Conflict of Interest/Intellectual Property No universal standards Commercialization Public trust

10. Complexity of Clinical Trials IRB issues Informed consent Changing regulations HIPAA Trial design

11. Clinic to Community – Barriers Public trust Communication Community involvement Cost

12. Where Do We Go From Here? Develop recommendations Deliver Report to President 2005/2006 Series–Focus Groups on Recommendations