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Presentation on theme: "Title Presenter name Slideshow-URL Conference name Date."— Presentation transcript:

1 Title Presenter name Slideshow-URL Conference name Date

2 Slideshow URL…………….. Researcher bias Positive result bias  20 teams do studies, 1 publishes p<0.05 Poorly explained analyses DOI: 10.1371/journal.pmed.0020124

3 DOI: 10.1371/journal.pmed.1001747 85% of research resources are wasted! We must... favor... unbiased, transparent, collaborative research with greater standardization Share data, protocols, materials, software, other tools

4 Supported by gov policy: e.g. UK and NIH MetaboLights repository  www.ebi.ac.uk/metabolights/ NIH Metabolomics Data Repository  www.metabolomicsworkbench.org/data/index.php ISA-Tab for metadata  http://www.isa-tools.org/format.html Data sharing

5 What about methods? http://reproducibility.cs.arizona.edu/ “The good news is that I was able to find some code. I am just hoping that it is a stable working version of the code... I have lost some data... The bad news is that the code is not commented and/or clean. So, I cannot really guarantee that you will enjoy playing with it.” 613 papers tested 123 successful reproductions

6 Problem There is a reproducibility crisis  Published results are untrustworthy  Research is a waste of government money (85%) What's the solution?  Share data AND methods

7 Thanks or summary Slideshow URL


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