1. Lessons learned about metals in the Estuary: The importance of long term clam accumulation data Cynthia L. Brown, Samuel N. Luoma, Francis Parchaso, Janet K.Thompson and Jeanne DiLeo U.S. Geological Survey

4. 25 mm

5. What we have learned from Potamocorbula and Macoma

6. 1.Do river inflows affect the bioavailability of different metals? 2.What is the influence of water chemistry (salinity)? 3.Can metal effects be separated from other influences in an environment this complex? 4.How does history affect interpretations of long term data sets?

7. 1.Do river inflows affect the bioavailability of different metals? 2.What is the influence of water chemistry (salinity)? 3.Can metal effects be separated from other influences in an environment this complex? 4.How does history affect interpretations of long term data sets?

8. Freshwater inflow is a primary influence on metal accumulation

13. 1.Do river inflows affect the bioavailability of different metals? 2.What is the influence of water chemistry (salinity)? 3.Can metal effects be separated from other influences in an environment this complex? 4.How does history affect interpretations of long term data sets?

14. Water chemistry (salinity) affects cadmium bioaccumulation

17. 1.Do river inflows affect the bioavailability of different metals? 2.What is the influence of water chemistry (salinity)? 3.Can metal effects be separated from other influences in an environment this complex? 4.How does history affect interpretations of long term data sets?

18. Detecting silver impacts in a complex estuary

21. Potamocorbula amurensis EggsSperm

24. 1.Do river inflows affect the bioavailability of different metals? 2.What is the influence of water chemistry (salinity)? 3.Can metal effects be separated from other influences in an environment this complex? 4.How does history affect interpretations of long term data sets?

25. The importance of a long term perspective

29. Contaminants bioaccumulate differently Metals cause detectable biological signals Integration of hydrodynamics, sediment dynamics, reproduction and geochemistry is essential to understanding processes in this complicated ecosystem.