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Reduction of Peritendinous Adhesions by Hydrogel Containing Biocompatible Phospholipid Polymer MPC for Tendon Repair by Noriyuki Ishiyama, Toru Moro, Takashi.

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Presentation on theme: "Reduction of Peritendinous Adhesions by Hydrogel Containing Biocompatible Phospholipid Polymer MPC for Tendon Repair by Noriyuki Ishiyama, Toru Moro, Takashi."— Presentation transcript:

1 Reduction of Peritendinous Adhesions by Hydrogel Containing Biocompatible Phospholipid Polymer MPC for Tendon Repair by Noriyuki Ishiyama, Toru Moro, Takashi Ohe, Toshiki Miura, Kazuhiko Ishihara, Tomohiro Konno, Tadashi Ohyama, Mizuna Kimura, Masayuki Kyomoto, Taku Saito, Kozo Nakamura, and Hiroshi Kawaguchi J Bone Joint Surg Am Volume 93(2):142-149 January 19, 2011 ©2011 by The Journal of Bone and Joint Surgery, Inc.

2 Photographs and bar graphs illustrating the effect of a local application of the MPC hydrogel (50 μL), formed from a mixture of PMBV (2.5% or 5.0%) and 2.5% PVA, on peritendinous adhesions and tendon healing in the rat Achilles tendon model. Noriyuki Ishiyama et al. J Bone Joint Surg Am 2011;93:142- 149 ©2011 by The Journal of Bone and Joint Surgery, Inc.

3 Photographs, photomicrographs, and bar graphs illustrating the effect of local application of MPC hydrogel (50 μL), formed from a mixture of 5.0% PMBV and 2.5% PVA, on peritendinous adhesions and tendon healing in the rabbit flexor digitorum profundus tendo... Noriyuki Ishiyama et al. J Bone Joint Surg Am 2011;93:142- 149 ©2011 by The Journal of Bone and Joint Surgery, Inc.

4 Assays for cell migration and viability were performed with use of fibroblastic NIH3T3 cells cultured in a double chamber dish divided by a porous membrane. Noriyuki Ishiyama et al. J Bone Joint Surg Am 2011;93:142- 149 ©2011 by The Journal of Bone and Joint Surgery, Inc.


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