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Chapter 11 Cell Communication. Local signaling: Paracrine Synaptic Long distance signaling: Hormonal. Chapter 11 Cell Communication.

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Presentation on theme: "Chapter 11 Cell Communication. Local signaling: Paracrine Synaptic Long distance signaling: Hormonal. Chapter 11 Cell Communication."— Presentation transcript:

1 Chapter 11 Cell Communication

2 Local signaling: Paracrine Synaptic Long distance signaling: Hormonal. Chapter 11 Cell Communication

3 Stage I: Reception Chapter 11 Cell Communication

4 Stage I: Reception Chapter 11 Cell Communication

5 Stage II: Transduction Chapter 11 Cell Communication

6 Stage II: Transduction Chapter 11 Cell Communication

7 Stage II: Transduction Chapter 11 Cell Communication

8 Stage II: Transduction Chapter 11 Cell Communication

9 Stage II: Transduction Chapter 11 Cell Communication

10 Stage II: Transduction Chapter 11 Cell Communication

11 Stage II: Transduction Chapter 11 Cell Communication

12 Stage II: Transduction Chapter 11 Cell Communication

13 Stage III: Response Chapter 11 Cell Communication

14 Stage III: Response Chapter 11 Cell Communication

15 Ligand: A molecule that binds specifically to another molecule. Chapter 11 Cell Communication

16 Three kinds of surface receptors: G-protein linked receptors Receptor tyrosine kinases Ion channel receptors (Kinase = enzyme that transfers phosphate groups.) Chapter 11 Cell Communication

17 G-protein linked receptors Chapter 11 Cell Communication

18 G-protein linked receptors Chapter 11 Cell Communication G-protein GDP GTP enzyme

19 G-protein linked receptors Chapter 11 Cell Communication G-protein enzyme GTP GDP

20 G-protein linked receptors Chapter 11 Cell Communication

21 G-protein linked receptors Chapter 11 Cell Communication

22 G-protein linked receptors Chapter 11 Cell Communication

23 G-protein linked receptors Chapter 11 Cell Communication

24 G-protein linked receptors Chapter 11 Cell Communication

25 G-protein linked receptors Chapter 11 Cell Communication

26 Receptor Tyrosine Kinase Chapter 11 Cell Communication

27 Receptor Tyrosine Kinase Chapter 11 Cell Communication ATP ATP ATP Tyr Relay proteins

28 Receptor Tyrosine Kinase Chapter 11 Cell Communication

29 Receptor Tyrosine Kinase Chapter 11 Cell Communication

30 Receptor Tyrosine Kinase Chapter 11 Cell Communication

31 Receptor Tyrosine Kinase Chapter 11 Cell Communication

32 Receptor Tyrosine Kinase Chapter 11 Cell Communication

33 Receptor Tyrosine Kinase Chapter 11 Cell Communication

34 Receptor Tyrosine Kinase Chapter 11 Cell Communication

35 Ion channel receptor Chapter 11 Cell Communication

36 Ion channel receptor Chapter 11 Cell Communication

37 Ion channel receptor Chapter 11 Cell Communication

38 Ion channel receptor Chapter 11 Cell Communication

39 Ion channel receptor Chapter 11 Cell Communication

40 Ion channel receptor Chapter 11 Cell Communication

41 Ion channel receptor Chapter 11 Cell Communication

42 Ion channel receptor Chapter 11 Cell Communication

43 Ion channel receptor Chapter 11 Cell Communication

44 Ion channel receptor Chapter 11 Cell Communication

45 Ion channel receptor Chapter 11 Cell Communication

46 Ion channel receptor Chapter 11 Cell Communication

47 A Phophosphorylation Cascade Chapter 11 Cell Communication

48 A Phophosphorylation Cascade Chapter 11 Cell Communication ATP Protein kinases Inactive protein Relay molecule

49 A Phophosphorylation Cascade Chapter 11 Cell Communication

50 A Phophosphorylation Cascade Chapter 11 Cell Communication

51 A Phophosphorylation Cascade Chapter 11 Cell Communication

52 A Phophosphorylation Cascade Chapter 11 Cell Communication

53 A Phophosphorylation Cascade Chapter 11 Cell Communication

54 A Phophosphorylation Cascade Chapter 11 Cell Communication

55 A Phophosphorylation Cascade Chapter 11 Cell Communication

56 A Phophosphorylation Cascade Chapter 11 Cell Communication

57 A Phophosphorylation Cascade Chapter 11 Cell Communication

58 A Phophosphorylation Cascade Chapter 11 Cell Communication

59 A Phophosphorylation Cascade Chapter 11 Cell Communication

60 A Phophosphorylation Cascade Chapter 11 Cell Communication

61 A Phophosphorylation Cascade Chapter 11 Cell Communication Why bother with such a complicated system?

62 A Phophosphorylation Cascade Chapter 11 Cell Communication

63 A Phophosphorylation Cascade Chapter 11 Cell Communication

64 A Phophosphorylation Cascade Chapter 11 Cell Communication

65 A Phophosphorylation Cascade Chapter 11 Cell Communication

66 A Phophosphorylation Cascade Chapter 11 Cell Communication

67 Scaffolding proteins and specificity Chapter 11 Cell Communication

68 Scaffolding proteins and specificity Chapter 11 Cell Communication

69 Scaffolding proteins and specificity Chapter 11 Cell Communication

70 Scaffolding proteins and specificity Chapter 11 Cell Communication

71 Scaffolding proteins and specificity Chapter 11 Cell Communication


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