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Nardella et al. Supplementary Fig. 1 Murine Rheb 0 0.5 1 1.5 wt Line 47 Line 50 Log gene expression (a.u.) ******* 200 bp Founders 474849505152597086878889.

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Presentation on theme: "Nardella et al. Supplementary Fig. 1 Murine Rheb 0 0.5 1 1.5 wt Line 47 Line 50 Log gene expression (a.u.) ******* 200 bp Founders 474849505152597086878889."— Presentation transcript:

1 Nardella et al. Supplementary Fig. 1 Murine Rheb 0 0.5 1 1.5 wt Line 47 Line 50 Log gene expression (a.u.) ******* 200 bp Founders 474849505152597086878889 90 91 A B C HA-Rheb 1234 1- Line 50 2- WT 3- Line 47 4- pcDNA3.1 HA-Rheb transfected HeLa cells

2 HA  -actin PIG HA-Rheb-PIG Nardella et al. Supplementary Fig. 2 0 5 10 15 20 25 30 PIG HA-Rheb-PIG Rapamycin Rheb + VehicleRheb + Rapamycin  -Gal + cells (%) + __ _ ++ + __ + _ + _

3 Nardella et al. Supplementary Fig. 3 Phospho-AktPten Pten +/- PB-Rheb;Pten +/- B WTPB-RhebPten +/- PB-Rheb; Pten +/- SA  -Gal pos. cells (%) 0 5 10 15 20 25 A 40X C WT PB-Rheb; Pten+/- PB-RhebPten +/- P-T389 S6K S6K

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