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Bell Work tRNA’s anticodons are complementary to mRNA’s codons when they meet in the ribosome, why is it important that they are the exact complement?

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Presentation on theme: "Bell Work tRNA’s anticodons are complementary to mRNA’s codons when they meet in the ribosome, why is it important that they are the exact complement?"— Presentation transcript:

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2 Bell Work tRNA’s anticodons are complementary to mRNA’s codons when they meet in the ribosome, why is it important that they are the exact complement?

3 Test Thursday!

4 Cut out the notes and glue them on page 43 2:001:591:581:571:561:551:541:531:521:511:501:491:481:471:461:451:441:431:421:411:401:391:381:371:361:351:341:331:321:311:301:291:281:271:261:251:241:231:221:211:201:191:181:171:161:151:141:131:121:111:101:091:081:071:061:051:041:031:021:011:000:590:580:570:560:550:540:530:520:510:500:490:480:470:460:450:440:430:420:410:400:390:380:370:360:350:340:330:320:310:300:290:280:270:260:250:240:230:220:210:200:190:180:170:160:150:140:130:120:110:100:090:080:070:060:050:040:030:020:01End

5 Title: Mutations Page:43 Date: 10/26/15 Standard: Identify and Illustrate changes in DNA and evaluate the significance of these changes EQ: How Do Mutations of DNA Affect the Outcome of a Protein?

6 Mutations: changes in the genetic material caused by mistakes during replication, transcription, or due to environmental factors (radiation) Sickle Cell Anemia Color Blindness Crystal clear underwater vision! Crystal clear underwater vision Resistance to HIV

7 Two major types of mutations: Point Mutations (substitutions) A mutation that changes a single base Frameshift Mutations An insetion or deletion that affects the entire amino acid sequence

8 Normal DNA Phe Tyr AlaArg DNA mRNA

9 Silent: DNA mRNA PheTyr Ala Arg Even though a base changes, it does not cause a change in the amino acids Point Mutation

10 Missense: DNA mRNA PheTyr Gly Arg A base change causes a change in one amino acid Point Mutation

11 Nonsense: DNA mRNA PheStop Ala Arg A base change causes an early stop Point Mutation

12 Insertion: DNA mRNA Phe IsoCysThr A base is added and causes a change in all the amino acids after it Frameshift Mutation

13 Deletion: DNA mRNA Phe LeuHis A base is deleted and causes a change in all the amino acids after it Frameshift Mutation

14 Box new base RED Color new codons Green Color New amino acids purple or blue

15 Quick Write (notecard): Which is more likely to have a bigger effect on an organism, a point mutation or frameshift mutation? Explain why.

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