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7.1 Chromosomes and Phenotype KEY CONCEPT The chromosomes on which genes are located can affect the expression of traits.
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7.1 Chromosomes and Phenotype Review-Two copies of each autosomal gene affect phenotype. Mendel studied autosomal gene traits, like hair texture. BUT Patterns of inheritance are often complex!
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7.1 Chromosomes and Phenotype Mendel’s rules of inheritance apply to autosomal genetic disorders. –A heterozygote for a recessive disorder is a carrier. –Disorders caused by dominant alleles are uncommon. (dominant)
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7.1 Chromosomes and Phenotype Males and females can differ in sex-linked traits. Genes on sex chromosomes are called sex-linked genes. –Y chromosome genes in mammals are responsible for male characteristics. –X chromosome genes in mammals affect many traits.
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7.1 Chromosomes and Phenotype Male mammals have an XY genotype. –All of a male’s sex- linked genes are expressed. –Males have no second copies of sex-linked genes.
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7.1 Chromosomes and Phenotype (1).X-linked traits or sex-linked traits. Studied by American Scientist-Thomas Hunt Morgan studied eye color of Drosophila melanogasta –fruit fly. A pattern of inheritance when traits are controlled on the sex chromosome, not on the autosomes (#1-22). If a male inherits the recessive trait on the x chromosome, the recessive trait will always be expressed. The Y chromosome has no corresponding allele for an x- linked trait. ( It is not there!) Two examples in humans are : Hemophilia and color blindness
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7.1 Chromosomes and Phenotype
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Female mammals have an XX genotype. (2)X chromosome inactivation randomly “turns off” one X chromosome which results in two types of cells- females can be black, orange, and white. X-white (both males and females), X0, orange, Xo- black
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