1. Dr. Howell Biology I Blacksburg High School

2. Look at diagram A below. What process is represented?

3. Look at diagrams B and C below. What is this called?

4. How many TOTAL chromosomes does a human have?

5. How many AUTOSOMES does a human have total?

6. How many SEX CHROMOSOMES does a human have?

7. What sex chromosomes does a male have? A female?

8. What is sickle cell disease?

9. Match the disease to its chromosomal disorder:

10. What sex is the individual in this karyotype?

11. What is a pedigree?

12. What does a square represent? What does a circle represent? What does a shaded shape mean? What does a horizontal line between two people mean? What does a vertical line coming off of married people mean? The children The person has the disease A male A female The are married In a pedigree:

13. What is/are the possible genotype(s) of individual # 3 below?

14. What is the possible genotype(s) of individual #12 below:

15. An autosomal recessive disorder means that the affected individuals will have what genotype? Could have any of the genotypes Either FF or Ff FF Ff ff

16. What genotype(s) does an individual with an autosomal dominant disease have? Could have any of these genotypes PP pp Pp Either PP or Pp

17. What is (are) the possible genotype(s) of individual #2?

18. What is (are) the possible genotype(s) of individual #7?

19. Which chromosome are most sex- linked genes found?

20. What sex – male or female – is most affected by sex-linked genes?

21. What is gene therapy?

22. What are polygenic traits?

23. What disease does this karyotype indicate?

26. What are some uses for DNA fingerprinting?

27. Who committed the crime?