1. Childhood and Adult Secondhand Smoke and Type 2 Diabetes in Women Featured Article: Martin Lajous, M.D., S.C.D., Laura Tondeur, M.S., Guy Fagherazzi, P.H.D., Blandine de Lauzon-Guillain, P.H.D., Marie-Christine Boutron-Ruaualt, M.D.,P.H.D. Fraçoise Clavel-Chapelon, P.H.D. Diabetes Care Volume 36: 2720-2725 September, 2013

2. STUDY OBJECTIVE To evaluate the relationship between childhood and adult secondhand smoke and type 2 diabetes Lajouls M. et al. Diabetes Care 2013;36:2720-2725

3. STUDY DESIGN AND METHODS Cohort subjects were 37,343 French women from the E3N- EPIC study Subjects never smoked and were free of type 2 diabetes, cancer, or cardiovascular disease at baseline in 1992 Self-reported childhood secondhand smoke exposure was defined as having at least one parent who smoked Adult secondhand smoke was defined as the sum of self- reported hours recorded at baseline of exposure to tobacco smoke from a spouse who smoked (or domestic close contact) and from outside the home Lajouls M. et al. Diabetes Care 2013;36:2720-2725

4. RESULTS Between 1992 and 2007, 795 cases of incident type 2 diabetes were identified and validated Women with at least one parent who smoked appeared to have an 18% higher rate of type 2 diabetes than women with parents who did not smoke Adult secondhand smoke exposure (no exposure vs. ≥4 h/day) was associated with an increased rate of type 2 diabetes Lajouls M. et al. Diabetes Care 2013;36:2720-2725

6. CONCLUSIONS Secondhand smoke exposure in childhood and adulthood is associated with a higher rate of type 2 diabetes Lajouls M. et al. Diabetes Care 2013;36:2720-2725