Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure S1 Figure S1. Search results of single nucleotide polymorphism (SNP) of rs466013 of the GRIK1 gene used in this study (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=466013).

Published byKellie Dickerson Modified over 8 years ago

Similar presentations

Presentation on theme: "Figure S1 Figure S1. Search results of single nucleotide polymorphism (SNP) of rs466013 of the GRIK1 gene used in this study (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=466013)."— Presentation transcript:

1 Figure S1 Figure S1. Search results of single nucleotide polymorphism (SNP) of rs466013 of the GRIK1 gene used in this study (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=466013). Above: Genomic location of rs466013 (pointed by red arrows; the NCBI Assembly database: GRCh37.p10 version). Down: Genomic location of rs466013 for 6 versions of the NCBI Assembly database (pointed by red arrows).

2 Figure S2 Figure S2. Search results of single nucleotide polymorphisms (SNPs) of rs466013, rs425507, rs388700 and rs402280 of the GRIK1 gene used in this study (http://genome.ucsc.edu/cgi- bin/hgTracks?db=hg18&position=chr21%3A30120300- 30129700&hgsid=370279953_3haDCdtlwLEpPqkcmUFYdaAFYNhx). Above: Genomic location of the GRIK1 gene. Down: Genomic location of rs466013, rs425507, rs388700 and rs402280 (pointed by red arrows; the NCBI Assembly database: NCBI36/hg18 version).

3 Figure S3 Figure S3. GRIK1 mRNA expression levels in peripheral blood mononuclear cells according to the GRIK1 SNPs (rs388700 and rs402280) genotypes. The relative GRIK1 expression was detected by quantitative real-time RT-PCR, and expression from individuals with TT+TA genotypes was compared to that from individuals with AA genotype. The GRIK1 (NM_000830.3) primer sequences were 5’- gcggttagagatggatcaaca-3’ (located at nucleotide 2559-2579 of the transcript (NM_000830.3) and 5’-tcatgaaagcccacatcttct-3’ (located at nucleotide 2617-2637 of the transcript (NM_000830.3)). The relative expression levels were expressed as GRIK1 mRNA/ HPRT mRNA ratio.

4 Figure S4 (European) (Japanese) (Taiwanese) Common elements in "Khor CC", "Onouchi Y" and "Lee YC": rs2233152 (MIA) Common elements in "Onouchi Y" and "Lee YC": rs2736340 (BLK) rs2618479 (BLK) rs6993775 (BLK) rs10401344 (ITPKC) rs4813003 (CD40) European Asian Figure S4. Venn diagram of 4 GWAS studies. Gene SNPs from 4 GWAS studies were used for searching for common gene SNPs by using Venny website (http://bioinfogp.cnb.csic.es/tools/venny/).

5 Figure S5 (Japanese) (Taiwanese) (Korean) Common elements in "Onouchi Y " and "Lee YC": rs2736340 (BLK) rs2618479 (BLK) rs6993775 (BLK) rs10401344 (ITPKC) rs2233152 (MIA) rs4813003 (CD40) Common elements in "Lee YC" and "Tsai FJ": rs4894410 (MRPS22) rs1873668 (MRPS22) rs4243399 (COPB2) rs1568657 (BTBD1) Asian Figure S5. Venn diagram of 4 GWAS studies. Gene SNPs from 4 GWAS studies were used for searching for common gene SNPs by using Venny website (http://bioinfogp.cnb.csic.es/tools/venny/).

Download ppt "Figure S1 Figure S1. Search results of single nucleotide polymorphism (SNP) of rs466013 of the GRIK1 gene used in this study (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=466013)."

Similar presentations

Lecture 2 Strachan and Read Chapter 13

Lecture 2 Strachan and Read Chapter 13
The Build-up of the Red Sequence at z

The Build-up of the Red Sequence at z
PCR-Based Genotyping Methods

PCR-Based Genotyping Methods
Predicting the Function of Single Nucleotide Polymorphisms Corey Harada Advisor: Eleazar Eskin.

Predicting the Function of Single Nucleotide Polymorphisms Corey Harada Advisor: Eleazar Eskin.
Biological Databases Chi-Cheng Lin, Ph.D. Associate Professor Department of Computer Science Winona State University – Rochester Center clin@winona.edu.

Biological Databases Chi-Cheng Lin, Ph.D. Associate Professor Department of Computer Science Winona State University – Rochester Center
Genome Browsers Ensembl (EBI, UK) and UCSC (Santa Cruz, California)

Genome Browsers Ensembl (EBI, UK) and UCSC (Santa Cruz, California)
DNA Sequencing and Gene Analysis

DNA Sequencing and Gene Analysis
How to access genomic information using Ensembl August 2005.

How to access genomic information using Ensembl August 2005.
Genome Browsers UCSC (Santa Cruz, California) and Ensembl (EBI, UK)

Genome Browsers UCSC (Santa Cruz, California) and Ensembl (EBI, UK)
“An integrated encyclopedia of DNA elements in the human genome” ENCODE Project Consortium. Nature 2012 Sep 6; 489:57-74. Michael M. Hoffman University.

“An integrated encyclopedia of DNA elements in the human genome” ENCODE Project Consortium. Nature 2012 Sep 6; 489: Michael M. Hoffman University.
Polymerase Chain Reaction WORKSHOP (3)

Polymerase Chain Reaction WORKSHOP (3)
Sporadic ALS and rs12608932 Amyotrophic lateral sclerosis Spoardic ALS estimated heritability: 0.35-0.85 Located in intron of UNC13A gene on chromosome.

Sporadic ALS and rs Amyotrophic lateral sclerosis Spoardic ALS estimated heritability: Located in intron of UNC13A gene on chromosome.
UCSC Genome Browser 1. The Progress 2 Database and Tool Explosion 3 2000 : 230 databases and tools 1996 : first annual compilation of databases and tools.

UCSC Genome Browser 1. The Progress 2 Database and Tool Explosion : 230 databases and tools 1996 : first annual compilation of databases and tools.
Chapter 25 Chapter 25 Genetic Determinants of Osteoporosis Copyright © 2013 Elsevier Inc. All rights reserved.

Chapter 25 Chapter 25 Genetic Determinants of Osteoporosis Copyright © 2013 Elsevier Inc. All rights reserved.
Biology 101 DNA: elegant simplicity A molecule consisting of two strands that wrap around each other to form a “twisted ladder” shape, with the.

Biology 101 DNA: elegant simplicity A molecule consisting of two strands that wrap around each other to form a “twisted ladder” shape, with the.
Online Mendelian Inheritance in Man (OMIM): What it is & What it can do for you Knowledge Management & Eskind Biomedical Library January 27, 2012 helen.

Online Mendelian Inheritance in Man (OMIM): What it is & What it can do for you Knowledge Management & Eskind Biomedical Library January 27, 2012 helen.
Biological databases Exercises. Discovery of distinct sequence databases using ensembl.

Biological databases Exercises. Discovery of distinct sequence databases using ensembl.
GVS: Genome Variation Server Materials prepared by: Warren C. Lathe, PhD www.openhelix.com Updated: Q2 2010 Version 2.

GVS: Genome Variation Server Materials prepared by: Warren C. Lathe, PhD Updated: Q Version 2.
Figure S1. Alignment of sequences from the 5′-end to the Sm binding site of reported genomic sequences (9-15) for HSUR 1. MicroRNA binding sites are.

Figure S1. Alignment of sequences from the 5′-end to the Sm binding site of reported genomic sequences (9-15) for HSUR 1. MicroRNA binding sites are.
Supplementary figure 1 Surface marker expression in % days A B Supplementary figure 1: Characterization of dmECFC and hECFC. ECFC clones showed a typical.

Supplementary figure 1 Surface marker expression in % days A B Supplementary figure 1: Characterization of dmECFC and hECFC. ECFC clones showed a typical.

Similar presentations

Ads by Google