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Can PET/CT and PET FDG predict Chemotherapy response in lung cancer patients? By: Megan Broscious.

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Presentation on theme: "Can PET/CT and PET FDG predict Chemotherapy response in lung cancer patients? By: Megan Broscious."— Presentation transcript:

1 Can PET/CT and PET FDG predict Chemotherapy response in lung cancer patients? By: Megan Broscious

2 Introduction: Cancer is the leading cause of death in the United States. Cancer is the leading cause of death in the United States. More people did from lung cancer than any other type of cancer. More people did from lung cancer than any other type of cancer. Not every patient responds to chemotherapy. Not every patient responds to chemotherapy.

3 Methods 100 male and 100 female cancer patients will be evaluated with PET/CT and or FDG PET to predict which patients will respond to treatment. 100 male and 100 female cancer patients will be evaluated with PET/CT and or FDG PET to predict which patients will respond to treatment. The 200 patients will be evaluated weekly for a period of 7 weeks, as they undergo 2 courses of docetaxel and carboplatin. The 200 patients will be evaluated weekly for a period of 7 weeks, as they undergo 2 courses of docetaxel and carboplatin. The prospective data will be attained by using a nominal level of measurement and a Chi-square Goodness-of-Fit statistical test. The prospective data will be attained by using a nominal level of measurement and a Chi-square Goodness-of-Fit statistical test.

4 Methods… A positive response will be represented by a negative slope and significantly different from zero. A positive response will be represented by a negative slope and significantly different from zero. A negative response will be represented by a positive slope or one that was not different from zero. A negative response will be represented by a positive slope or one that was not different from zero. The patients will then be followed for one year to see if the results were correct. The patients will then be followed for one year to see if the results were correct.

5 Results The results of several conducted studies show that PET/CT and or FDG PET can potentially predict which patients will respond to treatments in week one and week three of chemotherapy. The results of several conducted studies show that PET/CT and or FDG PET can potentially predict which patients will respond to treatments in week one and week three of chemotherapy.

6 Implications With this new technology, patients will have the option to cease chemotherapy if they are not responding, saving them from the grueling side effects of chemotherapy. With this new technology, patients will have the option to cease chemotherapy if they are not responding, saving them from the grueling side effects of chemotherapy. Patients also have the option to select a new treatment plan. Patients also have the option to select a new treatment plan.

7 Costs: PET scans are more costly than other diagnostic imaging scans. PET scans are more costly than other diagnostic imaging scans.

8 Conclusion More studies are needed to completely validate the results of these studies. With this in mind, according to studies done, PET/CT and or FDG PET do have the ability to predict chemotherapy response in lung cancer patients. More studies are needed to completely validate the results of these studies. With this in mind, according to studies done, PET/CT and or FDG PET do have the ability to predict chemotherapy response in lung cancer patients.


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