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Clayton Wiley MD/PhD. The patient is a 72-year-old male who presents with bitemporal hemianopsia without endocrine abnormalities. Diagram bitemporal hemianopsia?

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Presentation on theme: "Clayton Wiley MD/PhD. The patient is a 72-year-old male who presents with bitemporal hemianopsia without endocrine abnormalities. Diagram bitemporal hemianopsia?"— Presentation transcript:

1 Clayton Wiley MD/PhD

2 The patient is a 72-year-old male who presents with bitemporal hemianopsia without endocrine abnormalities. Diagram bitemporal hemianopsia? Question 1

3 www.dwp.gov.uk

4 Coronal T1

5 Coronal +Contrast

6 Sagittal +contrast

7 What is the differential diagnosis based on MRI/age. Question 2

8 Suprasellar lesions include: Aneurysm Dermoid/epidermoid cyst Craniopharyngioma Granular cell tumor Hypophysitis Hypothalamic neuronal hamartoma Meningioma Metastasis Optic glioma Pituitary macroadenoma Rathke's cyst Xanthogranuloma Answer

9 The surgeon performs an endoscopic endonasal biopsy, and an intraoperative evaluation is requested. Describe the cytologic features of the smear. Click here to view slide.here Question 3

10 The patient undergoes resection. Review the permanent section. Describe the histologic features of this lesion. Click here to view slide.here Question 5

11 What is your final diagnosis? Question 6

12 Craniopharyngioma, adamantinomatous-type Answer

13 What is the corresponding WHO grade of this lesion? Question 8

14 WHO grade I Answer

15 How would you expect this material to appear grossly? Question 10

16 Thick brownish-yellow fluid, like machine oil, possibly with crumbly debris. Answer

17 From what embryologic structure is this tumor presumed to develop? Question 11

18 Rathke pouch epithelium Answer


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