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The Chain of Infection
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The various ways infection can be transmitted.
As healthcare professionals, it is important to understand two facts about infection: The various ways infection can be transmitted. 2. The ways the infection chain can be broken.
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There are six links in the chain of infection: 1. Causative agent 2
There are six links in the chain of infection: 1. Causative agent 2. Source or reservoir 3. Portal of exit 4. Mode of transmission 5. Portal of entry 6. Susceptible host
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1st - The Infectious Agent
-Any disease-causing microorganism (pathogen)
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Microorganism A small, living plant or animal not visible to the naked eye
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Pathogens vs. Nonpathogens
Nonpathogens are beneficial microorganisms that are found on and in the human body Pathogens cause disease/infection
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Class I - Bacteria Multiply rapidly
Classified by shape and arrangement
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Cocci Round or spherical in shape
If Cocci occur in pairs they are diplococci If Cocci occur in chains they are streptococci If Cocci occur in clusters or groups they are staphylococci
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Cocci Cocci are the most common pus-producing microorganisms
Diplococci bacteria cause diseases such as Gonorrhea, Meningitis, & Pneumonia. Streptococci bacteria cause diseases such as Strep throat and Rheumatic fever.
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Staphylococci Can cause infections such as Boils Wound infections
Toxic shock
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Bacilli Rod shaped Occur singly, in pairs, or in chains
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Bacilli Many bacilli contain flagella, threadlike projections that are similar to tails and allow organisms to move Bacilli have the ability to form spores, thick walled capsules. In the spore form, bacilli are extremely difficult to kill.
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Diseases caused by different types of bacilli include:
Tuberculosis Tetanus Pertussis Whooping cough Botulism Diphtheria Typhoid
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Class II - Protozoa one-celled animals often found in decayed materials and contaminated water.
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Class III - Fungi simple, plantlike organisms that live on dead organic matter.
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Two common fungi forms:
Yeasts Molds
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Fungi cause diseases such as:
Ringworm Athlete’s foot Histoplasmosis Thrush
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Class IV - Rickettsiae (ri-ket-se-a) parasitic microorganisms which means they cannot live outside the cells of another living organism. Commonly found in fleas, lice, ticks, mites
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Rickettsiae transmitted to humans by the bites of these insects (typhus fever, rocky mountain spotted fever).
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Class V - Viruses Difficult to kill because they are resistant to many disinfectants and antibiotics. Smallest microorganism Cause diseases such as Common cold Measles, Mumps Influenza Chicken pox Warts
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-The organism in which the infectious microbes reside
2nd - The Reservoir Host -The organism in which the infectious microbes reside
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What are “Carrier Hosts?”
Hosts that do not show any outward signs or symptoms of a disease, but are still capable of transmitting the disease are known as carriers.
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-Route of escape of the pathogen from the reservoir
3rd - The Portal of Exit -Route of escape of the pathogen from the reservoir Examples: respiratory secretions, blood exposure, breaks in skin
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4th - The Route of Transmission
Method by which the pathogen gets from the reservoir to the new host direct contact air insects
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5th - The Portal of Entry Route through which the pathogen enters its new host Respiratory System (inhalation) Gastrointestinal System (ingestion) Urinary & Reproductive Tracts (sexual contact) Breaks in Skin (Protective Barrier)
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6th - The Susceptible Host
The organism that accepts the pathogen The support of pathogen life and its reproduction depend on the degree of the host’s resistance. Organisms with strong immune systems are better able to fend off pathogens. Organisms with weakened immune systems are more vulnerable to the support and reproduction of pathogens.
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How to interrupt the chain of infection:
Pathogen Identification: identify infectious agent and appropriate treatment Asepsis and Hygiene: potential hosts and carriers must practice asepsis and maintain proper personal hygiene Control Portals of Exit: Healthcare personnel must practice standard precautions (Control body secretions and wash hands according to protocol.) -
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4. Prevent a Route of Transmission
Prevent direct or indirect contact by Proper hand washing Disinfection & sterilization techniques Isolation of infected patients Not working when contagious
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5. Protect Portal of Entry
Healthcare professionals must make sure that ports of entry are not subjected to pathogens. (nose, mouth, eyes, open wounds, etc.)
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6. Recognition of Susceptible Host
Healthcare professionals must recognize and protect high-risk patients. Cancer Patients AIDS Patients Transplant Patients Infants Elderly Patients
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“Remember--breaking the chain of infection is the responsibility
of each healthcare professional.”
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