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Rational Design of Small Molecule Inhibitors Targeting RhoA Subfamily Rho GTPases Xun Shang, Fillipo Marchioni, Nisha Sipes, Chris R. Evelyn, Moran Jerabek-Willemsen,

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Presentation on theme: "Rational Design of Small Molecule Inhibitors Targeting RhoA Subfamily Rho GTPases Xun Shang, Fillipo Marchioni, Nisha Sipes, Chris R. Evelyn, Moran Jerabek-Willemsen,"— Presentation transcript:

1 Rational Design of Small Molecule Inhibitors Targeting RhoA Subfamily Rho GTPases Xun Shang, Fillipo Marchioni, Nisha Sipes, Chris R. Evelyn, Moran Jerabek-Willemsen, Stefan Duhr, William Seibel, Matthew Wortman, Yi Zheng Chemistry & Biology Volume 19, Issue 6, Pages 699-710 (June 2012) DOI: 10.1016/j.chembiol.2012.05.009 Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

2 Figure 1 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

3 Figure 2 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

4 Figure 3 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

5 Figure 4 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

6 Figure 5 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

7 Figure 6 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

8 Figure 7 Chemistry & Biology 2012 19, 699-710DOI: (10.1016/j.chembiol.2012.05.009) Copyright © 2012 Elsevier Ltd Terms and Conditions Terms and Conditions

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