1. DNA Structure & Replication Key Terms CSCOPE Unit 06 Lesson 01

2. DNA  Deoxyribonucleic acid  Double-stranded nucleic acid (double helix shape—like a twisted ladder)  Contains genetic information for cell functions, growth, and division.

3. Nucleotide  Basic building block of nucleic acids  Three parts:  Sugar  Phosphate group  Nitrogen base

4. Deoxyribose Sugar  Sugar component in the backbone of DNA  5-Carbon sugar

5. Phosphate Group  Binds with sugar in DNA backbone  Phosphorous attached to four oxygen atoms

6. Nitrogen Base Pairs  Nitrogen base pairs form the “rungs” of the DNA structure.  Adenine  Purine base that pairs with thymine  Thymine  Pyrimidine base that pairs with adenine  Cytosine  Pyrimidine base that pairs with guanine  Guanine  Purine base that pairs with cytosine

7. DNA Puzzle Pieces  What do you notice about the structure overall?  What does it look like?  How do the two sides of the “ladder” compare?  What are the rungs of the “ladder” made of?  Which nucleic acid pairs with which?  In what ways do you think the real DNA in each person’s cells is the same as the model?  In what ways do you think it is different than the model?