1. Specific Immunity By Tanner Hamilton, Asia Thofield

2. The Immune System

3. What The Immune System

4. How it works Proteins on cell surface Immune memory

5. Innate Immune System General defense Usually bacterial infections

6. Adaptive Immune System Learned throughout life Specific Immunity Usually used against bacteria and viruses that change regularly Quicker responses

7. T Cells Type of white blood cell Makes up adaptive immune system

8. Killer T-Cells Attacks other cells Can “see” into other cells Also known as “Cytotoxic”

9. Helper T-Cells Leads other T-Cells, B-cells, and other immune response cells Express CD4 co-receptor

10. General Facts about T-Cells Cause of all autoimmune responses Cause of transplanted organ rejection Some allergic reactions 1/50 T-Cells are actually found in blood

11. Development of a T-Cell Created in Lymph Nodes Matures in Thymus

12. HIV Infection occurs when bodily fluids are exchanged Human Immunodeficiency Virus

13. How HIV Reproduces Uses CD4 Cells Inserts genetic information into the host cells nucleus Reassembles itself and then pushes out of the host cell while stealing necessary components

14. How HIV affects T-Cells and The Body Undetermined cause of death for the T-Cell Lowers T-Cell count to dangerous levels Healthy adult= 500 cells/mm3 to 1,200 cells/mm3 HIV infected adult= Less than 200 cell/mm3 Can cause acquired immune deficiency syndrome

15. References http://www.webmd.com/a-to-z- guides/components-of-the-immune-systemhttp://www.webmd.com/a-to-z- guides/components-of-the-immune-system http://www.tcells.org/beginners/tcells/ https://www.aids.gov/hiv-aids-basics/just- diagnosed-with-hiv-aids/understand-your-test- results/cd4-count/https://www.aids.gov/hiv-aids-basics/just- diagnosed-with-hiv-aids/understand-your-test- results/cd4-count/ http://www.the- scientist.com/?articles.view/articleNo/38739/tit le/How-HIV-Destroys-Immune-Cells/http://www.the- scientist.com/?articles.view/articleNo/38739/tit le/How-HIV-Destroys-Immune-Cells/