1. 8.3 DNA Replication KEY CONCEPT General Description: DNA replication copies the genetic information of a cell.

2. 8.3 DNA Replication Replication copies the genetic information. A single strand of DNA serves as a template for a new strand. The rules of base pairing direct replication. DNA is replicated during the S (synthesis) stage of the cell cycle. Each body cell gets a complete set of identical DNA.

3. 8.3 DNA Replication Proteins carry out the process of replication. DNA serves only as a template. Enzymes and other proteins do the actual work of replication. Process 1. Enzymes unzip the double helix. (DNA Helicase) 2. Free-floating nucleotides form hydrogen bonds with the template strand. nucleotide The DNA molecule unzips in both directions.

4. 8.3 DNA Replication 3. DNA polymerase enzymes bond the nucleotides together to form the double helix. - DNA polymerases can find and correct errors. 3. DNA polymerase 4. new strand 2. Nucleotide 1. Sugar Phosphate Backbone

5. 8.3 DNA Replication DNA replication is semi-conservative, meaning one original strand and one new strand. original strand new strand Two molecules of DNA 4. Two new molecules of DNA are formed, each with an original strand and a newly formed strand.

6. 8.3 DNA Replication There are many origins of replication in eukaryotic chromosomes. DNA replication starts at many points in eukaryotic chromosomes. Replication is fast and accurate.

7. 8.3 DNA Replication How does replication conserve genetic information? Each parent or original strand of DNA serves as a template, allowing 2 identical strands of DNA to be made. This means the information “stays” the same or is “conserved”. https://www.youtube.com/watch?v=zdDkiRw1PdU

8. 8.3 DNA Replication https://www.youtube.com/watch?v=z685FFqmrpo