1. Lycopene Group 13

2. 茄紅素

3. Clinical trials Lycopene In Preventing of Prostate Cancer Condition: Prostate Cancer Lycopene In Preventing of Prostate Cancer Lycopene in Treating Patients With Metastatic Prostate Cancer Conditions: stage IV prostate cancer; recurrent prostate cancer Lycopene in Treating Patients With Metastatic Prostate Cancer Lycopene in Preventing Prostate Cancer in Healthy Participants Condition: Prostate Cancer Lycopene in Preventing Prostate Cancer in Healthy Participants Isoflavones Compared With Lycopene Before Surgery in Treating Patients With Stage I or Stage II Prostate Cancer Conditions: stage I prostate cancer; stage II prostate cancer Isoflavones Compared With Lycopene Before Surgery in Treating Patients With Stage I or Stage II Prostate Cancer

4. Lycopene Acyclic carotenoid (A family of natural pigments found in plants and animals) A powerful (?) antioxidant (Böhm et al 2002) Prevention of cardiovascular disease and cancer (Kohlmeier et al. 1997; Giovannucci 1999)

5. FoodFood Form Amount (mg/100g) Amount mg per serving Serving Size ApricotsFresh0.0050.007140 g ApricotsCanned, drained0.0650.091140 g ApricotsDried0.860.3440 g ChiliProcessed1.08-2.621.40-3.41130 g GrapefruitPink, fresh3.364.70140g GuavaPink, fresh5.407.56140 g Guava juicePink, processed3.348.35240 ml - 250 g KetchupProcessed16.603.321 tbsp. - 20 g PapayaRed, fresh2.00-5.302.8-7.421409.00 Pizza sauceCanned12.7115.89125 g Pizza sauceFrom pizza32.899.867slice - 30 g Rosehip pureeCanned0.780.4760 g SalsaProcessed9.283.712 tbsp. - 40 g Spaghetti sauceProcessed17.5021.88125 g TomatoesRed, fresh3.1-7.744.03-10.06130 g Tomatoes Whole, peeled, processed 11.2114,01125 g Tomato juiceProcessed7.8319,58240 mL - 250 g Tomato soupCanned, condensed3.999.77245 g Tomato pasteCanned30.079.0230 g WatermelonRed, fresh4.1011.48280 g

6. Higher bioavailability of lycopene in heated or processed food. (Agarwal and Rao 1998; Porrini and Riso 2000) Lipids in the diet increase the absorption of lycopene Metabolism

8. Biosynthetic pathway Glucose Pyruvate + G3P 1-deoxy-D-xylulose 5-phosphate (DXP) Acetyl-CoA Mevalonate Isopentenyl diphosphate (IPP) Dimethyallyl-PP (DMAPP) GPP FPP GGPP Lycopene

10. D-1-deoxyxylulose 5-phosphate synthase (DXS)

12. Hydroxymethylglutaryl-CoA synthase

13. Farnesyltranstransferase. (Geranylgeranyl-diphosphate synthase )