1. Circulatory System the organ system responsible for transporting nutrients and waste to and from cells Digestive System the body system that breaks down food using physical and chemical digestion and absorbs nutrients

2. Endocrine System the system of glands that secrete hormones into the bloodstream to regulate the body and keep homeostasis Excretory System the body system that filters and removes wastes from an organism

3. Integumentary System an organ system with multiple functions including protection and homeostasis Muscular System the system responsible for generating internal and external motion

4. Nervous System the body system that coordinates responses to internal and external stimuli Reproductive System the body systems that produce gametes, allow fertilization to occur, and lead to the development of offspring

5. Respiratory System the organ system that delivers oxygen to the body and removes carbon dioxide Skeletal System the organ system that provides physical support, stores essential minerals, and synthesizes new blood cells