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Necator americanus and Ancylostoma duodenale
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It has been estimated that greater than 2 billion people are infected with soil- transmitted helminths 880 million are children Up to 740 million are infected with Hookworms Warm, moist regions Regions of poor sanitation Regions lacking proper water filtration Thrive in impoverished regions
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Proportion of children who qualify for protective drug treatment
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Diarrhea Loss of appetite Malaise Intestinal obstructions Initial itching or rash at the site of penetration Intestinal bleeding leading to anemia and iron loss Reduced absorption of micronutrients and proteins Cognitive impairments and the stunting of growth
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They average a length of 500-600 µm.
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Stool samples conducted over three consecutive days and plated on two different agar plates for prevalence measurements.
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Eggs have an average length and width of 60-75 µm by 35-40 µm
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Albendazole Mebendadole Pyrantel pamoate Iron supplements if anemic
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Multi-drug therapy to combat several STH Preventative therapy for at risk communities WHO recommends once a year treatment for communities with greater than 20% prevalence and twice a year for greater than 50% More benefits in pregnancy than the alternative
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Knopp S, Mgeni AF, Khamis IS, Steinmann P, Stothard JR, et al. (2008) Diagnosis of Soil-Transmitted Helminths in the Era of Preventive Chemotherapy: Effect of Multiple Stool Sampling and Use of Different Diagnostic Techniques. PLoS Negl Trop Dis 2(11): e331. doi:10.1371/journal.pntd.0000331 Ndibazza J, Mpairwe H, Webb EL, Mawa PA, Nampijja M, Muhangi L, et al. Impact of anthelminthic treatment in pregnancy and childhood on immunisations, infections and eczema in childhood: a randomised controlled trial. PLoS One (2012) 7(12):e50325.10.1371/journal.pone.0050325 http://www.who.int/intestinal_worms/en/ http://www.who.int/intestinal_worms/en/ http://www.ncbi.nlm.nih.gov/pubmed/23598487 http://www.ncbi.nlm.nih.gov/pubmed/23598487 http://en.wikipedia.org/wiki/Pyrantel_pamoate http://en.wikipedia.org/wiki/Pyrantel_pamoate http://www.rxlist.com/albenza-drug.htm http://www.rxlist.com/albenza-drug.htm http://www.cdc.gov/parasites/hookworm/biology.html http://www.cdc.gov/parasites/hookworm/biology.html
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