1. Registration, Evaluation, Authorisation and Restriction of Chemical substances (REACH) – electronic support system Bc. Kryštof Dibusz Institute of Chemical Technology, Prague Applied Informatics in Chemistry email: dibuszk@vscht.cz

2. Introductory outline REACH review Why REACH? Electronic support system – development – features Conclusion & future plans

3. REACH review Most important EU chemical Regulation Equally applied in all 27 EU member states Entered into force – June 1, 2007 Protect human health and environment REACH procedures Costs (€2.3 billion) & Benefits (€50 billion)

4. Why REACH? Most important EU chemical Regulation Huge – 300 pages Available only in PDF or HTML Difficult information retrieval – time = money REACH Online system – features

5. REACH transformation From invalid HTML to valid XML XSLT, Python – regular expressions Result XML document – 15,000 lines – structured (Titles, Chapters, Articles) – annexes

6. REACH Online – development Python – OOP language Django – Python web framework – platform independent – database independent SQLite3 – SQL database engine – single file – portable

7. REACH Online – features Search – full-text, compound Related articles cross references Interactive table of contents On-line / Off-line version (installation wizard) User friendly design

13. Conclusion Transformation into electronic form REACH Online system Market gap Additional search – Smiles, InChI Lingual version (Czech)

14. Thank you for your attention Supervisor: Ing. Miloslav Nič, PhD.