1. Dominance: Co-Dominance, Incomplete Dominance and Blood Types

2. Lesson Objectives Minds ON Yesterday’s Recap Dominances and Blood Types Blood Typing Lab Success Criteria Homework Take Up New homework

3. Minds ON Two rabbits are heterozygous. Brown fur (B) is dominant to white fur (b). Dwarf (small) ears (D) are dominant to floppy ears (d). Draw a Punnett square showing the possibilities. We’ll do it together on the board once you’ve tried it.

4. Yesterday’s Recap Dihybrid Crosses Refers to the crossing of two individuals who are both heterozygous for TWO traits (e.g. PpTt x PpTt) Assumes that these traits are on different genes and can occur at the same time. E.g. Pod colour and seed colour

5. Dihybrid Crosses Parent 1 genotype is: AaBb Parent 2 genotype is: AaBb

6. Dominances So far, we have been looking at situations where a dominant trait completely masks the allele Bb/BB = dominant for purple colour

7. Incomplete Dominance Occurs when: -Neither gene is dominant or recessive -The gene effect is mixed - We use 2 different letters for the homologous pair since neither is dominant.

8. An Example of Incomplete Dominance With red and white snapdragons, the dominant allele that codes for the colour red is not completely dominant over the recessive allele that produces the white colour. The result is a pink flower.

9. Using a Punnett Square Red Flower – RR White Flower – WW R = 100% Pink Offspring xWW RRW R

10. Co-Dominance Occurs when: -Neither gene is dominant or recessive -Gene effects are NOT mixed -Therefore, both genes are expressed at the same time! -Examples: Roan cow or Camelia flower

11. An Example of Co-Dominance Write C (for co-dominance) and a super script (R=Red, W=white) Red haired = CRCR White haired = CWCW Red and White (Roan) =CRCW

12. Using a Punnett Square Red haired = CRCR White haired = CWCW Red and White (Roan) =CRCW = 100% Roan X

13. Blood Types – A Special Case There are three alleles: IA (Type A), IB (Type B) and i (Type O) – A and B are co-dominant – O is recessive +/- is the Rh (Rhesus) factor (if the Rh blood antigen is present, the person is Rh+; if not, they are Rh-) Predict offspring bloodtypes for: Heterozygous type A mother, type O father

14. Using A Punnett Square X i i ii i IA (Type A), IB (Type B) and i (Type O) -A and B are co-dominant -O is recessive 50% = A 5-% = O

15. Blood Types TypesDistributionRatios O+ 1 person in 338.4% O- 1 person in 157.7% A+ 1 person in 332.3% A- 1 person in 166.5% B+ 1 person in 129.4% B- 1 person in 671.7% AB+ 1 person in 293.2% AB- 1 person in 167 0.7% AB universal plasma donors AB+ universal recipients O+ blood most needed O- universal RBC donor

16. Rhesus Disease An individual either has, or does not have, the "Rhesus factor" on the surface of their red blood cells. The status is usually indicated by Rh positive (Rh+ does have the D antigen) or Rh negative (Rh− does not have the D antigen) suffix to the ABO blood type. Rhesus Disease occurs when there is incompatibility between blood types of mother and fetus. Untreated, the result can cause death of the child. Occurs in second and later pregnancies

17. Murder Mystery Lab “I THINK THERE’S BEEN…(sunglasses on)..AN ACCIDENT!” (with emphasis) https://www.youtube.com/watch?v=mznsEcZlM 2I&noredirect=1 The Jim Carrey shows us… https://www.youtube.com/watch?v=HJSqkwyL1 Zo

18. Lab There’s been a murder. Hortatio needs your help! You have to find out who did it. Agglutination: refers to the clumping effect of blood when it is mixed with Anti-A, Anti-B or Rh serum. Go around to each station and sample the blood to find out the blood type and Rh factor to determine who killed One-Eyed Earl!