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Radiological scoring in Psoriatic Arthritis
Application of the OMERACT filter to four scoring methods
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Radiological scoring methods for PsA
Four methods described Modified Steinbrocker Ratingen method for PsA Sharp method for PsA Sharp/van der Heijde method for PsA All originally developed and tested for RA Addition of DIPs of the hands as a scoring site
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Specific features in radiographs of PsA
Joint pattern DIPs and PIPs, asymmetric and frequently in a ray-pattern Wrist and isolated ray Symmetrical as in RA Features Destruction (widening, osteolysis, pencil-in-cup) Proliferation (shaft metacarpal/tarsal, adjacent to joints, ankylosis)
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Comparison of sites/features included in scoring
modified Steinbrocker Ratingen Sharp Sharp/van der Heijde Films hands/feet Erosions JSN Malalignment Proliferation Global - X Range 0-160 0-360 0-470 0-528
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Methods: OMERACT filter
Truth : does the method measure what it should measure? Discrimination: Reliability, discrimination between patients, and sensitivity to change over time Feasibility Boers J Rheumatol 1998;25:198-9
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Application in clinical trials
Sharp and Sharp/van der Heijde method Proven sensitivity to change over short periods of time (24 – 52 weeks) Addition of DIPs of little extra value Trial duration too short to pick up change in pencil in cup, tuft resorption, periostitis, osteolysis
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Plan for OMERACT 8 Scoring of the radiographs of IMPACT 1 by four different methods Involvement of developers of all methods Information on discrimintation Test-retest reliability Sensitivity to change Information on feasibility
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