1. J. Alozy, S. George, F.Murtas, M. Silari 1 CERN 17-06-2014 GEMPIX detectors as hadron therapy beam monitors and radioactive waste detectors GEMPIX construction Beam monitor for Hadrotherapy GEMPIX for Radioactive Waste Conclusions F.Murtas INFN-CERN-Ardent J. Alozy, E.Frojdh, S. George, M. Silari CERN

2. J. Alozy, S. George, F.Murtas, M. Silari 2 CERN 17-06-2014 Gempix Detector Side view Quad medipix board The detector has two main parts : - The quad medipix without silicon sensors - The triple gem detector with HV filters and connector New HV GEM board

3. J. Alozy, S. George, F.Murtas, M. Silari 3 CERN 17-06-2014 Gem foils and frames A new GEM layout has been designed Active area of 28x28 mm 2 The electordes path have been designed to avoid the medipix wire bonding. Produced by Rui De Oliveira. New frames were designed 10x10 cm 2 to fit the holes of the Quadmedipix board 5 different thickness (from 1 to 5 mm) Wire bonding position

4. J. Alozy, S. George, F.Murtas, M. Silari 4 CERN 17-06-2014 Assembling the GEM foils The three GEM foils are assembled on top of HV GEM board

5. J. Alozy, S. George, F.Murtas, M. Silari 5 CERN 17-06-2014 Final detector

6. J. Alozy, S. George, F.Murtas, M. Silari 6 CERN 17-06-2014 Head on detector Gas flux AR CO 2 or AR CO 2 CF 4 The anode is a quad naked without silicon sensor : The active area is 9 cm 2 Triple GEM Mylar window Particles to be analysed HVGEM Console FITPIX Console HV FITPIX

7. J. Alozy, S. George, F.Murtas, M. Silari 7 CERN 17-06-2014 A small TPC Gas flux The anode is a quad medipix without silicon sensor: The active area is 9 cm 2 The particle track is analysed with 512 pixel in length of 3 cm This detector could be used also as Tissue Equivalent Proportional Chamber The track path is equivalent to 30 microns of tissue … with 17 samples/microns Triple GEM Kapton window Particles to be analysed Length analysed

8. J. Alozy, S. George, F.Murtas, M. Silari 8 CERN 17-06-2014 GEMPIX Detectors Head-on version (4 detectors) Side-on version (2 detectors ) HV Connector Medipix DAQ box

9. J. Alozy, S. George, F.Murtas, M. Silari 9 CERN 17-06-2014 Measurements at CNAO (Pavia - Italy) Carbon ion beam at 480 Mev/nucleon

10. J. Alozy, S. George, F.Murtas, M. Silari 10 CERN 17-06-2014 Measurements Beam : 480 MeV/A Carbon Ion Measurements in air Measurements in water phantom : 23 different depths throughout water phantom Each position given spot 5.10 8 carbon ion treatment (clinical treatment intensities) Frame length = 1ms, gas = ArCO 2, gain = 750 V (~0.43 keV/TOT - Proper calibration awaits the return of the detector from CNAO RP).

11. J. Alozy, S. George, F.Murtas, M. Silari 11 CERN 17-06-2014 Mylar window Gas in/out Fitpix Readout External HV (HVGEM) GEMPIX at CNAO (Pavia)

12. J. Alozy, S. George, F.Murtas, M. Silari 12 CERN 17-06-2014 GEMPIX as a Beam Monitor 480 MeV/A carbon ions, 10 ms frame, ASIC in Medipix (particle counting) Mode, IKrum = 5 Counts Single Carbon Ion Other particle

13. J. Alozy, S. George, F.Murtas, M. Silari 13 CERN 17-06-2014 The overall beam shape is clearly visible Beam profile As number of hits As energy released

14. J. Alozy, S. George, F.Murtas, M. Silari 14 CERN 17-06-2014 Gempix Linearity Number of counts per spills Time (s)

15. J. Alozy, S. George, F.Murtas, M. Silari 15 CERN 17-06-2014 Phantom used at CNAO Bragg Peak finder at CNAO Thin Window Gempix Stepper Motor Several measurement of energy deposition along the beam (5x10 8 Carbon ions per 10 spills)

16. J. Alozy, S. George, F.Murtas, M. Silari 16 CERN 17-06-2014 Energy deposition is ~0.43 keV/TOT Spot width here is sigma of gaussian (FWHM = 2.3 sigma) Depth profile and beam dimension

17. J. Alozy, S. George, F.Murtas, M. Silari 17 CERN 17-06-2014 LinearLog3D reconstruction Energy deposition: 3D reconstruction This part (neutrons and gammas) could be analyzed with really high resolution

18. J. Alozy, S. George, F.Murtas, M. Silari 18 CERN 17-06-2014 Single Event Upset Depth = 124 mm (in bragg peak), ~0.43 keV/Count (9.6 MHz, TOT mode), IKrum = 1, 1ms frame SEU Events

19. J. Alozy, S. George, F.Murtas, M. Silari 19 CERN 17-06-2014 No Cfg Resets Reset at start Reset/10 frames Reset every frame Reconfiguring

20. J. Alozy, S. George, F.Murtas, M. Silari 20 CERN 17-06-2014 Radioactive Waste : a detector for 55 Fe

21. J. Alozy, S. George, F.Murtas, M. Silari 21 CERN 17-06-2014 Sample Preparation Fraiseuse DECKEL FP4M for powder production reducing the 60 CO background Boxes supplied by SMIPA s.r.l Dimension: 38x38x4 mm 3 (now 38x38x8 mm 3 ) Weight: 3.951 ± 0.15% Measurements for Fe-55 concentration with GEMPIX, two different configuration : Drift gap 11 mm Drift gap 3 mm Support conceived for measurements with samples and calibration sources

22. J. Alozy, S. George, F.Murtas, M. Silari 22 CERN 17-06-2014 Radioactive waste: 55 Fe 1 sec radioactive source 100s counts

23. J. Alozy, S. George, F.Murtas, M. Silari 23 CERN 17-06-2014 X-ray candidates Bck Signal vs Background Gas AR CO 2 CF 4 Gate: 1 s HV 1200 V Gas flux: 3.5 l/h Clk: 24 Ikrum: 5 Polarization: -

24. J. Alozy, S. George, F.Murtas, M. Silari 24 CERN 17-06-2014 Cluster parameters measurements Cluster type Cluster volume Inner size Border size Size Size y vs size x 55 Fe 60 Co 55 Fe 60 Co 55 Fe 60 Co 55 Fe 60 Co 55 Fe 60 Co

25. J. Alozy, S. George, F.Murtas, M. Silari 25 CERN 17-06-2014 Online analysis Once that the calibration values are set in the Python script, an online analysis can be performed Number of X-Rays measured in 1000 sec Number of big blob Cut on size Cut on charge

26. J. Alozy, S. George, F.Murtas, M. Silari 26 CERN 17-06-2014 Drift 3 mm vs drift 11 mm Attenuation length 2.91 cm Theory: 11 mm/ 3 mm = 2.6 Measurements: 11 mm/ 3 mm = 2.7 Waiting the measurements from certificated company for the final calibration

27. J. Alozy, S. George, F.Murtas, M. Silari 27 CERN 17-06-2014 Summary Six GEMpix detectors have been built and they show good performances from single particle detections to high intensity beam monitor Really good cluster analysis is possible thanks to the Fitpix software pakage Software tools and detector tuning are still needed for the cluster analysis in gas (dE/dX, particle id, 3D track reconstruction....) The detector could be easily improved with Timepix3 chips Other applications and measurements are scheduled for next months Monitor for burning plasma (KSTAR - PETAL) Measurements for micro and nano dosimetry with tissue equivalent gas Monitor for gamma radiotherapy