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The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease by Koon-Hou Mak, Deepak L. Bhatt,

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Presentation on theme: "The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease by Koon-Hou Mak, Deepak L. Bhatt,"— Presentation transcript:

1 The influence of body mass index on mortality and bleeding among patients with or at high-risk of atherothrombotic disease by Koon-Hou Mak, Deepak L. Bhatt, Mingyuan Shao, Steven M. Haffner, Christian W. Hamm, Graeme J. Hankey, S. Claiborne Johnston, Gilles Montalescot, Philippe Gabriel Steg, Steven R. Steinhubl, Keith A.A. Fox, and Eric J. Topol EHJ Volume 30(7):857-865 April 1, 2009 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

2 Kaplan–Meier estimates of the cumulative incidence of all-cause mortality for the body mass index quartiles. Koon-Hou Mak et al. Eur Heart J 2009;30:857-865 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

3 Four-knot plot of estimated spline transformation and 95% confidence interval for the endpoint of unadjusted (A) and adjusted (B) all-cause mortality. Koon-Hou Mak et al. Eur Heart J 2009;30:857-865 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org

4 Subgroup analysis for the efficacy endpoints and safety endpoints log-transformed body mass index (BMI) was applied in the unadjusted Cox proportional hazards models. Koon-Hou Mak et al. Eur Heart J 2009;30:857-865 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2009. For permissions please email: journals.permissions@oxfordjournals.org


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