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Bone Morphogenetic Protein-7 Modulates Genes that Maintain the Vascular Smooth Muscle Cell Phenotype in Culture by Haimanti Dorai, and T Kuber Sampath.

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Presentation on theme: "Bone Morphogenetic Protein-7 Modulates Genes that Maintain the Vascular Smooth Muscle Cell Phenotype in Culture by Haimanti Dorai, and T Kuber Sampath."— Presentation transcript:

1 Bone Morphogenetic Protein-7 Modulates Genes that Maintain the Vascular Smooth Muscle Cell Phenotype in Culture by Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am Volume 83(1 suppl 1):S70-S78 March 1, 2001 ©2001 by The Journal of Bone and Joint Surgery, Inc.

2 Effect of bone morphogenetic protein-7 (BMP-7), transforming growth factor-beta (TGF-β), and platelet-derived growth factor-BB (PDGF-BB) on human aortic smooth muscle cell proliferation. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

3 Effect of bone morphogenetic protein-7 (BMP-7) on p21 expression in platelet-derived growth factor (PDGF)-treated human aortic smooth muscle cultures. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

4 Fig. 3 Genes induced by bone morphogenetic protein-7 (BMP-7) in human aortic smooth muscle cells. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

5 Fig. 3 Genes induced by bone morphogenetic protein-7 (BMP-7) in human aortic smooth muscle cells. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

6 Fig. 4 Effect of bone morphogenetic protein-7 (BMP-7) on the endogenous and interleukin-1b (IL- 1b)-induced intercellular adhesion molecule-1 (ICAM-1). Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

7 Fig. 4 Effect of bone morphogenetic protein-7 (BMP-7) on the endogenous and interleukin-1b (IL- 1b)-induced intercellular adhesion molecule-1 (ICAM-1). Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

8 Fig. 5 Effect of bone morphogenetic protein-7 (BMP-7) on the expression of smooth muscle cell markers. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

9 Fig. 5 Effect of bone morphogenetic protein-7 (BMP-7) on the expression of smooth muscle cell markers. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

10 Fig. 5 Effect of bone morphogenetic protein-7 (BMP-7) on the expression of smooth muscle cell markers. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

11 Fig. 5 Effect of bone morphogenetic protein-7 (BMP-7) on the expression of smooth muscle cell markers. Haimanti Dorai, and T Kuber Sampath J Bone Joint Surg Am 2001;83:S70-S78 ©2001 by The Journal of Bone and Joint Surgery, Inc.

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