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Published byJames Hunter Modified over 9 years ago
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Integration architecture Queryable sources that generate XML Distributed queries over sources Query Manager to manage queries Saved queries as sources that can also be queried Leads to potential for query networks
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vSPARQL Service vSPARQL Service RDF Store RDF Store
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vSPARQL Service vSPARQL Service RDF Store RDF Store
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vSPARQL Service vSPARQL Service RDF Store RDF Store
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QM DB vSPARQL Service vSPARQL Service QM Server QM Client RDF Store RDF Store
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QM DB vSPARQL Service vSPARQL Service QM Server QM Client RDF Store RDF Store
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XML BIRN fMRI Study Label using Talairach Demon Extract centers of activation BIRN fMRI Study Schizophrenics vs Healthy Controls
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XML
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QM DB vSPARQL Service vSPARQL Service QM Server RDF/ OWL XML QM Client RDF Store RDF Store
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server RDF/ OWL XML QM Client RDF Store RDF Store
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server RDF/ OWL QM Client RDF Store RDF Store XML
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server RDF/ OWL QE Service QE Service QM Client RDF Store RDF Store XML
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server RDF/ OWL QE Service QE Service QM Client RDF Store RDF Store XML
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server XML RDF/ OWL QE Service QE Service QM Client RDF Store RDF Store XML
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Region FilteredHealthy (Red) Schizo- phrenic (Yellow) Dorso_lateral prefrontal cortex 552530 Brodmann area 6213107106 Frontal lobe575288287 N=1741
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QM DB vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service QM Server QE Service QE Service QM Client RDF Store RDF Store
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QM DB Remote Services Remote Services vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service Other Services Other Services QM Server Other Client XML RDF/ OWL XML QE Service QE Service Other Client QM Client RDF Store RDF Store RDF/ OWL Remote Services Remote Services
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Remote Services Remote Services vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service Other Services Other Services Other Client XML RDF/ OWL XML Other Client QM Client RDF Store RDF Store RDF/ OWL Remote Services Remote Services Query Manager Core Query Manager Core
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Remote Services Remote Services vSPARQL Service vSPARQL Service DXQuery Service DXQuery Service Other Services Other Services Other Client XML RDF/ OWL XML Other Client QM Client QM Client RDF Store RDF Store RDF/ OWL Remote Services Remote Services Query Manager Core Query Manager Core Query Manager Core with Plugins
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Remote Services Remote Services Other Client Remote Services Remote Services Query Manager Query Manager RDF/ OWL XML
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Query Manager Query Manager RDF/ OWL XML
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Query Manager Query Manager BIRN fMRI and FMA BIRN fMRI FMA
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Query Manager Query Manager BIRN fMRI, VBM and FMA BIRN fMRI FMA VBM
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Query Manager Query Manager Electronic Data Capture and Freezer Management Freezer Management EDC
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Query Manager Query Manager Biorepositories Biorepository
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Query Manager Query Manager Human Studies Database Clinical Trials Metadata Ontology of Clinical Research
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Query Manager Query Manager Ontology Views Ontology
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Query Manager Query Manager Summary
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Issues Response time Reliability Security Discoverability Usability Integration with other systems and methods
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Query Manager Query Manager Query Manager Query Manager Future Work
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Query Manager Query Manager Query Manager Query Manager Query Manager Query Manager
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BIRN fMRI FMA Brain Imaging View
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EDC Clinical View
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Clinical Imagin g Clinical/I maging View
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Genomic View Gene Protein Others….
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Clinical/I maging Genomic Translational View
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Query Web
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Translational Medicine
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Web Semantic Web Internet Query Web A Network-centric view of information systems
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Bin Zhang
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A convergence? Biology as an information science Information science as biology Networks as the link
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Credits Todd Detwiler Onard Mejino Joshua Franklin Ron Shaker Xenia Hertzenberg Nolan Nichols Marianne Shaw Wayne Warren Linda Shapiro Dan Suciu Cornelius Rosse Funding: NLM, NIMH, NHLBI
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