1. Risk of GI Bleed on NSAIDs Professor Michael Langman International Ibuprofen Foundation University of Birmingham, UK

2. Table 1 Case Characteristics of the Three Studies Statistic British Catalan Swedish # Cases/Controls 1131/2114 875/2626 466/1137 Age (Mean  SD) 74 ± 7.8 58 ± 17.1 64 ±15.2 % Male/Female 56/44 69/31 53/47 % Hx UGI Problems 40 36 0

3. Odds Ratios (95% C.I.) According to Drug (Not Dose Restricted) Note: The upper 95% C.I. bound for Piroxicam is 21.8 ; the odds ratio for Keto is 34.9 with an upper 95% C.I. bound of 96.5. 1

4. Odds Ratios (95% C.I.) According to Dose of Drug (mg) APAPDiclof.Ibu Note: Values exceeding 15 are truncated at 15 1

5. Odds Ratios (95% C.I.) According to Dose of Drug (mg) IndomethNaproxenPiroxicam Note: Values exceeding 15 are truncated at 15 1

6. Odds Ratios (95% C.I.) According to Dose of Drug (mg) APAPDiclof.IbuIndomethNaproxenPiroxicam Note: Values exceeding 15 are truncated at 15 1