1. TLR Funnel plot (according to outcomes) for studies included in the meta-analysis Death A TVR B MACE DC 0.01 0.1 1 10 100 0.0 0.4 0.8 1.2 1.6 SE(log OR) OR 0.01 0.1 1 10 100 0.0 0.2 0.4 0.6 0.8 SE(log OR) OR 0.01 0.1 1 10 100 0.0 0.4 0.8 1.2 1.6 SE(log OR) OR 0.01 0.1 1 10 100 0.0 0.4 0.8 1.2 1.6 SE(log OR) OR

2. Funnel plot (according to outcomes) for studies included in the meta-analysis SUPPLEMENTAL FIGURE 1 MI E Stent Thrombosis F 0.01 0.1 1 10 100 0.0 0.4 0.8 1.2 1.6 SE(log OR) OR 0.01 0.1 1 10 100 0.0 0.4 0.8 1.2 1.6 SE(log OR) OR

3. Odds Ratios of All Cause Mortality SUPPLEMENTAL FIGURE 2

4. SUPPLEMENTAL FIGURE 3 Odds Ratios of Target Lesion Revascularization

5. SUPPLEMENTAL FIGURE 4 Odds Ratios of Target Vessel Revascularization

6. SUPPLEMENTAL FIGURE 5 Odds Ratios of Major Adverse Cardiac Events