1. Featuring Bifurcation Trans-Radial Approach Technical Issues Martial Hamon Caen, France Provisionnal T stenting With the Frontier stent Main Branch Balloon 2.5mm3.0mm3.5mm4.0mm Side Branch Balloon 2.0mm2.5mm (7 French compatible device; stent length of main branch 18 mm) GUIDANT

2. Featuring Bifurcation Trans-Radial Approach Case Procedure LAD Diago. Wiring 2 vessels After Kissing Balloon dilation Placement of The Frontier stent

3. Featuring Bifurcation Trans-Radial Approach Frontier implantation Provisionnal T stenting Final Result Case Procedure Direct stenting of side branch Simutaneous kissing procedure

4. Featuring Bifurcation Trans-Radial Approach Case Procedure BeforeAfter Provisionnal T stenting With the Frontier stent

5. Featuring Bifurcation Trans-Radial Approach Designed for preserving side branch access Integrated-tip design allows single tip delivery, avoiding wire wrap Stent deploys with simultaneous “kissing balloon inflation” Wire position is maintained in both branches throughout the procedure Guidant MUTI-LINK FRONTIER™ Coronary Bifurcation Stent System Stent Description

6. Featuring Bifurcation Trans-Radial Approach Lesion selection and preparation Lesion type: to be avoided calcified vessels Tortuous vessels very small vessels. Preparation of lesion Pre-dilate the lesion(s) Keep 2 wires in place after pre-dilatation, to facilitate your exchange wire placement through the OTW lumen (buddy wire technique). Technical Issues Materials ≥ 7 French guiding catheter recommended Long guide wire for side branch access (extra-support preferred) The nominal diameter is the distal diameter of the device. The proximal diameter is 0.6 to 0.8 mm larger.

7. Featuring Bifurcation Trans-Radial Approach Manipulation Do not torque the system. It is NOT designed to respond to torque Remove the mandrel when the integrated tip is near the carina Once mandrel is removed, do not push the system forward without a second guide wire in the OTW lumen emerging distally. Use the middle balloon marker for good placement of the Frontier stent at the carina. Observe the relative position of the two guide wires, as parallel wires with clear divergence at the carina indicate optimal positioning prior to deployment. Do not pull back un-deployed Frontier system through guiding catheter. If needed, pull back entire system with the guiding catheter as a single unit. Post-dilate with kissing balloons if result is not optimal following Frontier deployment. Technical Issues