1. Ebola E. coli Fungus from soil Phage virus Exam #3 W 4/7 (bring your cheat sheet) Q&A on T 4/8 at 6-8pm in SZB 104 mini-quiz posted this afternoon

2. The Immune System Non-specific: –barriers Specific : –B-cells -> antibodies –T-cells Fig 43.2

3. Specific Immune System Overview Fig 43.16

4. Antibodies recognize and bind to antigens Fig 43.10

5. Fig 43.14 Each B-cell/antibody recognizes a specific antigen

6. Marked for destruction by WBC B-cells make antibodies that bind to antigens marking them for destruction Fig 43.19

7. Fig 43.21 Antibody binding to antigens can lead to... Neutralization Engulf and Destroy

8. What about damaged or abnormal cells? Viral infections Cancer cells Non-functional cells

9. T-cells recognize and destroy abnormal cells Fig 43.18

10. Specific Immune System Overview Fig 43.16

11. Fig 43.15 It can take 7-14 days to produce sufficient antibodies to eliminate a pathogen

12. Memory B-cells make the response to a second exposure more rapid This is how vaccines work. Fig 43.14

13. Vaccines work via memory B-cells that make the response to a second exposure more rapid Fig 43.15

14. When politics and science collide...

15. Human Papilloma Virus

16. Human Papilloma Virus: the leading cause of Genital warts Cervical cancer

17. At least 50% of sexually active people will get HPV at some time in their lives. Every year in the United States, about 6.2 million people get HPV. HPV is most common in young women and men who are in their late teens and early 20s. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

18. The American Cancer Society estimates that in 2006, over 9,700 women were diagnosed with cervical cancer and 3,700 women died from this cancer in the U.S. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

19. The HPV vaccine developed by Merck, Gardasil, protects against four HPV types which account for 70% of cervical cancers and 90% of genital warts. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

20. The HPV vaccine is made up of proteins from the outer coat of the virus. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7 Human Papilloma Virus: the leading cause of Genital warts Cervical cancer

21. The Texas Department of Health has ruled that students must be current with immunizations in order to attend school unless an exemption has been filed with the school in accordance with Texas Education Code, Health and Safety, Chapter 38.0001.

22. Current mandated vaccines for attendance in Texas schools: 3 doses of DPT, DTaP, DT, Td. 4 doses of Polio 1 dose of Measles on/after 1st birthday and 1 dose MMR on/after 1st birthday. 3 doses of Hepatitis B 1 dose of Varicella on/after 1st birthday (if the child has NOT had chickenpox)

23. The HPV vaccine is recommended for 11-12 year-old girls, and can be given to girls as young as 9. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

24. The HPV vaccine is recommended for 11- 12 year-old girls, and can be given to girls as young as 9. For the vaccine to be effective, you must be vaccinated prior to exposure to HPV. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

25. Effectiveness of HPV vaccine against cervical cancer

26. Effectiveness of HPV vaccine against genital warts

27. The length of vaccine protection (immunity) is usually not known when a vaccine is first introduced. So far, studies have followed women for five years and found that women are still protected. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

28. The length of vaccine protection (immunity) is usually not known when a vaccine is first introduced. So far, studies have followed women for five years and found that women are still protected. More research is being done to find out how long protection will last, and if a booster vaccine is needed years later. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

29. The retail price of the vaccine is $120 per dose ($360 for full series). While some insurance companies may cover the vaccine, others may not. http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine.htm#hpvvac7

30. Controversy http://www.youtube.com/watch?v=J1Zg46JKDzM

31. Ebola E. coli Fungus from soil Phage virus Exam #3 W 4/7 (bring your cheat sheet) Q&A on T 4/8 at 6-8pm in SZB 104 mini-quiz posted this afternoon